1430823-88-3

Basic information

• Product Name: C₄₀H₆₃NO₈Si
• Synonyms: C₄₀H₆₃NO₈Si
• CAS NO: 1430823-88-3
• Molecular Weight: 714.028
• Mol File: 1430823-88-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₀H₆₃NO₈Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₀H₆₃NO₈Si(1430823-88-3)
• EPA Substance Registry System: C₄₀H₆₃NO₈Si(1430823-88-3)

Safety Data

• Hazardous Substances Data: 1430823-88-3(Hazardous Substances Data)

Upstream product

• 149814-40-4 (2S,4R)-1-(tert-butoxycarbonyl)-4-((tert-butyldimethylsilyl)oxy)pyrrolidine-2-carboxylic acid 
• 465-20-3 bufalin 

Relevant articles and documents

Synthesis and structure-activity relationships study of cytotoxic bufalin 3-nitrogen-containing-ester derivatives

A series of bufalin 3-nitrogen-containing-ester derivatives (2-6) were designed, synthesized, and evaluated for their proliferation inhibition activities against human cervical epithelial adenocarcinoma (HeLa) and non-small-cell lung cancer (A549) cell lines. The structure-activity relationships (SARs) of this new series were described in this paper. Cytotoxicity data revealed that C3 moiety had important influence on cytotoxic activity. On two cell lines, the bufalin-3-piperidinyl-4-carboxylate compound 2 (IC50 values on HeLa and A549 cell lines were 0.76 nM and 0.34 nM, respectively) displayed a significant cytotoxic potency compared to the parent compound bufalin.