1432671-39-0

Basic information

• Product Name: 1-(3-methoxycarbonylbenzyl)-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione
• Synonyms: 1-(3-methoxycarbonylbenzyl)-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione
• CAS NO: 1432671-39-0
• Molecular Weight: 314.341
• Mol File: 1432671-39-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-methoxycarbonylbenzyl)-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-methoxycarbonylbenzyl)-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione(1432671-39-0)
• EPA Substance Registry System: 1-(3-methoxycarbonylbenzyl)-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione(1432671-39-0)

Safety Data

• Hazardous Substances Data: 1432671-39-0(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 35042-48-9 5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione 
• 1129-28-8 3-methoxycarbonylbenzyl bromide 

Downstream Products

• 1432671-40-3 1-(3-carboxybenzyl)-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione 
• 1432670-89-7 1-(3-(4-(pyrimidin-2-yl)piperazine-1-carbonyl)benzyl)-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione 

Relevant articles and documents

1-(Arylmethyl)-5,6,7,8-tetrahydroquinazolline-2,4-diones and Analogs and the Use Thereof

Disclosed are novel 1-(arylmethyl)-5,6,7,8-tetrahydroquinazoline-2,4-diones and analogs thereof, represented by the Formula I, wherein Ar, A, B, R3-R6 are defined herein. Compounds having Formula I are PARP inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of PARP activity, such as cancer.