1433174-92-5

Basic information

• Product Name: N-methoxy-3-(4-methoxyphenyl)-N-methylpropiolamide
• Synonyms: N-methoxy-3-(4-methoxyphenyl)-N-methylpropiolamide
• CAS NO: 1433174-92-5
• Molecular Weight: 219.24
• Mol File: 1433174-92-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-methoxy-3-(4-methoxyphenyl)-N-methylpropiolamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methoxy-3-(4-methoxyphenyl)-N-methylpropiolamide(1433174-92-5)
• EPA Substance Registry System: N-methoxy-3-(4-methoxyphenyl)-N-methylpropiolamide(1433174-92-5)

Safety Data

• Hazardous Substances Data: 1433174-92-5(Hazardous Substances Data)

Upstream product

• 2227-57-8 3-(4-methoxyphenyl)propynoic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 123707-27-7 N-methoxyurea-N,N',N'-trimethylurea 
• 768-60-5 4-methoxyphenylacetylen 

Downstream Products

• 1433175-08-6 C₂₄H₁₉NO₃ 
• 882866-44-6 3-iodo-2-(4'-methoxyphenyl)-quinolin-4(1H)-one 

Relevant articles and documents

Controlling the α/γ-Reactivity of Vinylogous Ketone Enolates in Organocatalytic Enantioselective Michael Reactions

The first regio-, diastereo-, and enantioselective direct Michael reaction of β,γ-unsaturated ketones with nitroolefins is enabled by Br?nsted base/hydrogen-bonding bifunctional catalysis. A squaramide-substituted tertiary amine catalyzes the reaction of a broad range of β,γ-unsaturated ketones to proceed at the α-site exclusively, giving rise to adducts with two consecutive tertiary carbon stereocenters in diastereomeric ratios of up to >20:1 and enantioselectivities generally in the 90–98 % ee range.