143410-89-3Relevant articles and documents
Inhibition of cyclic nucleotide phosphodiesterase by derivatives of 1,3- bis(cyclopropylmethyl)xanthine
Buckle,Arch,Connolly,Fenwick,Foster,Murray,Readshaw,Smallridge,Smith
, p. 476 - 485 (2007/10/02)
Alkylation of the selective type IV phosphodiesterase inhibitor, 8-amino- 1,3-bis(cyclopropylmethyl)-xanthine (1, BRL 61063), led exclusively to the N- 7 substituted derivatives 2-9, which showed varying selectivities for the PDE type IV isoenzyme relativ