14343-92-1

Basic information

• Product Name: 10-benzylideneanthracen-9(10H)-one
• Synonyms: 10-Benzylideneanthracen-9(10H)-one; 9(10H)-Anthracenone, 10-(phenylmethylene)-
• CAS NO: 14343-92-1
• Molecular Formula: C₂₁H₁₄O
• Molecular Weight: 282.3353
• Mol File: 14343-92-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 433.6°C at 760 mmHg
• Flash Point: 190.4°C
• Density: 1.225g/cm³
• Vapor Pressure: 1.01E-07mmHg at 25°C
• Refractive Index: 1.701
• CAS DataBase Reference: 10-benzylideneanthracen-9(10H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 10-benzylideneanthracen-9(10H)-one(14343-92-1)
• EPA Substance Registry System: 10-benzylideneanthracen-9(10H)-one(14343-92-1)

Safety Data

• Hazardous Substances Data: 14343-92-1(Hazardous Substances Data)

Usage

Chemical structure

A polycyclic aromatic compound with a benzylidene group attached to an anthracene core.

Appearance

Bright yellow solid.

Uses

a. Production of vat dyes for the textile industry.
b. Starting material in the synthesis of various organic compounds.
c. Photochemical sensitizer in the production of photodynamic therapy agents.

Toxicity

Moderately toxic.

Health effects

Studied for potential mutagenic and cytotoxic effects.

Additional applications

a. Investigated as a fluorescent material.
b. Used as an intermediate in the synthesis of organic electronics.

Upstream product

• 64-17-5 ethanol 
• 74975-71-6 10-bromo-10-(α-bromobenzyl)anthrone 
• 90-44-8 anthracen-9(10H)-one 
• 100-52-7 benzaldehyde 
• 78787-97-0 10-hydroxy-10-benzyl-9(10H)-anthracenone 
• 75-36-5 acetyl chloride 
• 529-86-2 9-anthrol 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 7664-93-9 sulfuric acid 
• 27094-21-9 benzyl-(10-benzyl-[9]anthryl)-ether 
• 144303-04-8 2-benzylidene-1-phenylbenzocyclobuten-1-ol 
• 17407-25-9 10-benzylidene-9,10-dihydro-[9]anthrol 
• 108-94-1 cyclohexanone 

Downstream Products

• 27094-23-1 acetic acid-(10-benzyl-[9]anthryl ester) 
• 73079-07-9 10-(4-chlorophenylimino)anthrone 
• 100606-18-6 10-chloro-10-(α-chlorobenzyl)anthrone 
• 67074-07-1 10-Benzyl-9,10-dihydro-[9]anthrol 
• 74975-68-1 10-(α-bromobenzylidene)anthrone 
• 2290-31-5 9-(α-Acetoxy-benzyl)-anthracen 
• 14344-30-0 9,10-dibenzylidene-9,10-dihydro-anthracene 
• 14344-31-1 1-Benzyliden-4-phenyl-2,3,6,7-dibenzo-cycloheptatrien-(2,4,6) 
• 7467-97-2 9-(α-bromo-benzyl)-10-phenyl-anthracene 
• 77033-03-5 (10-phenylanthracen-9-yl)benzyl chloride 
• 67856-09-1 (10-phenylanthracen-9-yl)benzyl alcohol 
• 2026-30-4 α-(9-anthryl)benzyl methyl ether 
• 72948-52-8 9-(1-hydroxybenzyl)-10-methylanthracene 
• 861300-73-4 10-Nitro-9-benzyl-9.10-dihydro-anthranol-⁽⁹⁾ 

Relevant articles and documents

Synthesis and antitumor activity of 10-substituted benzylidene anthrone

Fifteen compounds of 10-substituted benzylidene anthrone were prepared with moderate yield by reaction of anthrone and substituted benzaldehydes under the presence of pyridine and piperidine as catalyst. Their antitumor activities in vitro were evaluated.

Characterization of a new class of androgen receptor antagonists with potential therapeutic application in advanced prostate cancer

The human androgen receptor plays a major role in the development and progression of prostate cancer and represents a well-established drug target. All clinically approved androgen receptor antagonists possess similar chemical structures and exhibit the s

Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization

A novel series of 10-benzylidene-9(10H)-anthracenones and 10-(phenylmethyl)-9(10H)-anthracenones were synthesized and evaluated for antiproliferative activity in an assay based on K562 leukemia cells. The 3-hydroxy-4-methoxybenzylidene analogue 9h was fou