143540-05-0 Usage
Description
2-(Hydroxymethyl)-1,4-piperazinedicarboxylic acid 1,4-bis(tert-butyl) ester, also known as Di-tert-butyl 2-(Hydroxymethyl) Piperazine-1,4-dicarboxylate, is an organic compound with a complex molecular structure. It is characterized by its hydroxymethyl and piperazinedicarboxylic acid functional groups, as well as its t-butyl ester moieties. 2-(Hydroxymethyl)-1,4-piperazinedicarboxylic acid 1,4-bis(tert-butyl) ester is known for its potential applications in the pharmaceutical industry, particularly in the development of inhibitors for specific enzymes.
Uses
Used in Pharmaceutical Industry:
2-(Hydroxymethyl)-1,4-piperazinedicarboxylic acid 1,4-bis(tert-butyl) ester is used as a key intermediate compound for the synthesis of LSD1 inhibitors. These inhibitors are important in the development of novel therapeutic strategies for various diseases, including cancer and neurological disorders. The compound's unique structure allows it to interact with the target enzyme, thereby modulating its activity and potentially leading to therapeutic benefits.
Used in Drug Development:
In the field of drug development, 2-(Hydroxymethyl)-1,4-piperazinedicarboxylic acid 1,4-bis(tert-butyl) ester serves as a valuable building block for the creation of new molecules with potential biological activities. Its versatile chemical structure enables researchers to modify and optimize its properties, leading to the discovery of new drugs with improved efficacy, selectivity, and safety profiles.
Used in Chemical Research:
2-(Hydroxymethyl)-1,4-piperazinedicarboxylic acid 1,4-bis(tert-butyl) ester is also utilized in chemical research as a model compound for studying various reaction mechanisms and exploring new synthetic routes. Its unique functional groups and structural features make it an interesting subject for academic and industrial research, potentially leading to the development of innovative chemical processes and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 143540-05-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,5,4 and 0 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 143540-05:
(8*1)+(7*4)+(6*3)+(5*5)+(4*4)+(3*0)+(2*0)+(1*5)=100
100 % 10 = 0
So 143540-05-0 is a valid CAS Registry Number.
143540-05-0Relevant articles and documents
Application of piperazine structure containing compound to preparation of LSD1 (Lysine Specific Demethylase 1) inhibitor
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, (2017/09/29)
The invention discloses application of a piperazine structure containing compound to the preparation of a histone lysine specific demethylase (LSD1) inhibitor. The structural general formula of the compound is as shown in the following descriptions (wherein, A is hydrogen, carbonyl or thiocarbonyl) or a configurational isomer and a pharmaceutical salt thereof, or is as shown in the following descriptions or a pharmaceutical salt thereof. The compound has an obvious inhibition effect on the LSD1, can be prepared into the LSD1 inhibitor, and is used for preventing and treating a disease related to the activity of the histone LSD1.
Tricyclic heterocyclic compound and use thereof
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Page/Page column 34, (2009/12/28)
The present invention provides a tricyclic heterocyclic compound having a serotonin 5-HT2C receptor activation action and the like. A 5-HT2C receptor activator containing a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof.
NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF
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Page/Page column 71-72; 73-74, (2008/06/13)
Disclosed are novel piperazine derivatives that act as agonists of the α7 nAChR. Also disclosed are phannaceutical compositions, methods of treating inflammatory conditions, methods of treating CNS disorders, methods for inhibiting cytokine release from mammalian cells and methods for the preparation of the novel compounds.