1435462-41-1Relevant articles and documents
Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors
Liu, Jia-Jia,Sun, Juan,Fang, Yun-Bin,Yang, Yong-An,Jiao, Rui-Hua,Zhu, Hai-Liang
, p. 998 - 1008 (2014/02/14)
A series of novel 4,5-dihydropyrazole derivatives (4a-4t), containing the dinitrobenzotrifluoride moiety, as DNA gyrase inhibitors were designed and synthesized. Based on the preliminary results, compounds 4d, 4h and 4t with potent inhibitory activity in