14374-55-1

Basic information

• Product Name: 5-(2-methoxyphenyl)pentan-1-ol
• Synonyms: 5-(2-methoxyphenyl)pentan-1-ol
• CAS NO: 14374-55-1
• Molecular Weight: 194.274
• Mol File: 14374-55-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(2-methoxyphenyl)pentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-methoxyphenyl)pentan-1-ol(14374-55-1)
• EPA Substance Registry System: 5-(2-methoxyphenyl)pentan-1-ol(14374-55-1)

Safety Data

• Hazardous Substances Data: 14374-55-1(Hazardous Substances Data)

Upstream product

• 55001-09-7 methyl 3-(2-methoxyphenyl)propanoate 
• 6342-77-4 2-methoxy-benzenepropanoic acid 
• 1011-54-7 2-methoxycinnamic acid 
• 643746-88-7 5-(2-methoxyphenyl)pentanoic acid ethyl ester 
• 70311-27-2 2-methoxybenzenepropanoic acid ethyl ester 
• 33877-05-3 ethyl 3-(2-methoxyphenyl)acrylate 
• 33538-83-9 3-(2-methoxyphenyl)propanal 
• 10493-37-5 3-(2-methoxyphenyl)propan-1-ol 
• 612-16-8 (2-methoxyphenyl)methanol 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 14374-61-9 1,12-Bis-(2-methoxyphenyl)-dodec-6-in 
• 14401-83-3 1,12-Bis-<2-methoxy-phenyl>-dodecen-(6) 
• 14605-33-5 1-Brom-5-<2-methoxy-phenyl>-pentan 

Relevant articles and documents

Synthesis, in vitro and in silico evaluation of diaryl heptanones as potential 5LOX enzyme inhibitors

A new series of diaryl heptanones (12a-q) were synthesized and their structures were confirmed by its 1H, 13C NMR and Mass spectral data. These analogs were evaluated for their anti-oxidant activity and potential to inhibit 5-lipoxygenase. Compounds 12k and 12o showed potent in vitro 5-lipoxygenase enzyme inhibitory activity with IC50 values of 22.2, 21.5 μM, which are comparable to curcumin (24.4 μM). Further they also have shown significant antioxidant activity. Molecular docking studies clearly showed correlation between binding energy and potency of these compounds.