1443665-00-6

Basic information

• Product Name: diethyl [2-(5-aminopentyl)-5-(benzylamino)-1,3-oxazol-4-yl]phosphonate
• Synonyms: diethyl [2-(5-aminopentyl)-5-(benzylamino)-1,3-oxazol-4-yl]phosphonate
• CAS NO: 1443665-00-6
• Molecular Weight: 395.439
• Mol File: 1443665-00-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl [2-(5-aminopentyl)-5-(benzylamino)-1,3-oxazol-4-yl]phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl [2-(5-aminopentyl)-5-(benzylamino)-1,3-oxazol-4-yl]phosphonate(1443665-00-6)
• EPA Substance Registry System: diethyl [2-(5-aminopentyl)-5-(benzylamino)-1,3-oxazol-4-yl]phosphonate(1443665-00-6)

Safety Data

• Hazardous Substances Data: 1443665-00-6(Hazardous Substances Data)

Upstream product

• 4443-26-9 6-phthalimidohexanoic acid 
• 1443664-95-6 diethyl [5-(benzylamino)-2-[5-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)pentyl]-1,3-oxazol-4-yl]phosphonate 
• 1443664-90-1 diethyl [2,2-dichloro-1-[6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexanamido]ethenyl]phosphonate 
• 1443664-80-9 6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(1,2,2,2-tetrachloroethyl)hexanamide 
• 1443664-77-4 6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-(2,2,2-trichloro-1-hydroxyethyl)hexanamide 
• 141391-34-6 6-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)hexanamide 

Relevant articles and documents

Synthesis of 5-amino-2-aminoalkyl-1,3-oxazol-4-ylphosphonic acid derivatives and their use in the preparation of phosphorylated peptidomimetics

Starting from phthalimidoalkanoylamines 1 (amino-protected derivatives of glycine, β-alanine, γ-amino butyric, δ-amino valeric, and ε-amino caproic acids), a facile synthetic method has been developed to obtain diethyl 5-alkyl(dialkyl)amino-2-aminoalkyl-1,3-oxazol-4-ylphosphonates 7, which have been further used in the preparation of phosphorylated peptidomimetics 10 and 12.