144476-58-4

Basic information

• Product Name: 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(4-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester
• CAS NO: 144476-58-4
• Molecular Formula: C21H24N2O7
• Mol File: 144476-58-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(4-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(4-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester(144476-58-4)
• EPA Substance Registry System: 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(4-nitrophenyl)-, 2-methoxyethyl 1-methylethyl ester(144476-58-4)

Safety Data

• Hazardous Substances Data: 144476-58-4(Hazardous Substances Data)

Upstream product

• 66085-59-4 nimodipin 

Relevant articles and documents

Polarographic study of the photodecomposition of nimodipine

Nimodipine, a calcium antagonist belonging to the dihydropyridine family, produces a well-defined polarographic peak due to the four-electron reduction of the nitro group. This peak was used to track the photodecomposition of nimodipine induced by UV light and daylight. Nimodipine was modified by UV irradiation with degradation following first-order kinetics. A degradation rate constant of 0.099 min-1, with a half-life of 7.78 min, for UV irradiation without a filter was obtained. Furthermore, a quantum yield of 1.32 x 10-3 molecules/quantum absorbed was measured with a chemical actinometer. The UV degradation product, which was isolated and identified, showed that irradiation of nimodipine causes oxidation of the dihydropyridine ring and transmutation of the nitro group in the nitrobenzene moiety.