14464-51-8

Basic information

• Product Name: Olean-12-ene-2alpha,3beta,28-triol
• Synonyms: Olean-12-ene-2alpha,3beta,28-triol;(2α,3β)- Olean-12-ene-2,3,28-triol;(2alpha,3beta)- Olean-12-ene-2,3,28-triol
• CAS NO: 14464-51-8
• Molecular Formula: C30H50 O3
• Molecular Weight: 458.72
• Product Categories: Pentacyclic Triterpenes
• Mol File: 14464-51-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Olean-12-ene-2alpha,3beta,28-triol(CAS DataBase Reference)
• NIST Chemistry Reference: Olean-12-ene-2alpha,3beta,28-triol(14464-51-8)
• EPA Substance Registry System: Olean-12-ene-2alpha,3beta,28-triol(14464-51-8)

Safety Data

• Hazardous Substances Data: 14464-51-8(Hazardous Substances Data)

Upstream product

• 4373-41-5 maslinic acid 
• 557765-95-4 C₃₁H₄₈O₆S 
• 22425-82-7 methyl maslinate 

Relevant articles and documents

Maslinic acid derivatives induce significant apoptosis in b16f10 murine melanoma cells

Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid), a natural dihydroxylated pentacyclic triterpene acid isolated from olive-pressing residues, has been investigated together with some of its derivatives regarding the induction of apoptosis in B16F10 melanoma cells. Some of the compounds tested are described in this work, but others come from previous studies. Ten of these derivatives induce over 80% of apoptosis, clearly promoting cell death in B16F10 melanoma. By contrast, the induction cell death through necrosis was very slightly significant with these compounds. These results indicate that maslinic acid derivatives are promising chemopreventive and chemotherapeutic agents.

STUDIES ON OXIDATI0N OF TRITERPENOIDS: PART VII. TRANSFORMATION OF OLEANANE AND URSANE SKELETONS TO 11α,12α-OXIDOTRITERPENOIDS WITH HYDROGEN PEROXIDE AND SELENIUM DIOXIDE AND THEIR CARBON-13 NMR DATA.

Hydrogen peroxide-selenium dioxide in t-butanol has been found to be a good reagent for the preparation of 11α,12α-oxidotriterpenoids of oleanane and ursane skeletons; whereas α-amyrin and β-amyrin acetates furnished 11α,12α-epoxyurs-14-en-3β-yl acetate (4c) and 11α,12α-epoxytaraxer-14-en-3β-yl acetate (4a) respectively, uvaol and ursolic acid/methyl ester gave 11α,12α-epoxyurs-28->13-olide-3β-ol (5d); erythrodiol (3c) and oleanolic acid (3b)/methyl ester (3d) afforded 11α,12α-epoxy-oleanan-28->13-olide-3β-ol (5); olean-12-en-2α,3β,28-yl triacetate (3j) on similar reaction furnished 11α,12α-epoxytaraxer-14-en-3β-ol-2α,28-yl diacetate (4d) and 11α,12α-epoxytaraxer-14-en-2α,3β-diol-28-ylacetate (4e).