144735-55-7

Basic information

• Product Name: 5-(2-(methoxycarbonyl)trans-ethenyl)-7-methoxy-2-(3'-methoxy-4'-(benzyloxy)phenyl)benzofuran

Upstream product

• 1486-53-9 4-(benzyloxy)-3-methoxybenzoic acid 
• 1486-52-8 3-methoxy-4-benzyloxybenzoyl chloride 
• 292638-85-8 acrylic acid methyl ester 
• 515814-05-8 2-[4-(benzyloxy)-3-methoxyphenyl]-5-bromo-7-methoxybenzofuran 
• 35090-64-3 2-hydroxy-3-methoxy-5-bromobenzyl alcohol 
• 5034-74-2 5-bromo-3-methoxysalicylaldehyde 
• 1835-11-6 4-benzyloxy-3-methoxyacetophenone 
• 146072-13-1 methyl 3-methoxy-4-hydroxy-5-bromo-cinnamate 
• 135040-84-5 cuprous (4-benzyloxy-3-methoxy)phenyl acetylide 
• 61222-88-6 methyl 3-methoxy-4-hydroxy-5-bromocinnamate 
• 144735-54-6 1-ethynyl-4-(benzyloxy)-3-methoxybenzene 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 121-33-5 vanillin 
• 100-39-0 benzyl bromide 

Downstream Products

• 144735-71-7 3-nitro-5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-(benzyloxy)phenyl)benzofuran 
• 144735-68-2 4-acetyl-5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-acetoxyphenyl)benzofuran 
• 144735-75-1 3-cyano-5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-acetoxyphenyl)benzofuran 
• 144735-65-9 5-(acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-acetoxyphenyl)benzofuran-3-carbaldehyde 
• 144735-58-0 5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-acetoxyphenyl)benzofuran 
• 144735-74-0 5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-3-carbaldoxime 
• 144735-72-8 3-nitro-5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 
• 144735-61-5 3-(hydroxymethyl)-5-(2-(methoxycarbonyl)ethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 
• 144735-62-6 5-(2-(methoxycarbonyl)ethyl)-7-methoxy-3-methyl-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 
• 144735-66-0 4-bromo-5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-3-carbaldehyde 
• 144735-59-1 5-(2-(methoxycarbonyl)ethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-3-carbaldehyde 
• 144735-69-3 4-acetyl-5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 
• 144735-60-4 5-(2-carboxyethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-3-carbaldehyde 
• 144735-73-9 3-nitro-5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran 

Relevant articles and documents

An alternate method for the synthesis of 2-aryl/alkyl-5-bromo-7-methoxy benzofurans; application to the synthesis of Egonol, Homoegonol, and analogs via Heck reaction

We herein report the general, versatile, and convenient method for the synthesis of 2-arly/alkyl-5-bromo-7-methoxy benzofurans from easily available o-Vanillin in five steps. These benzofurans was successfully converted into biological active natural products Egonol, Homoegonol, and analogous on applying Heck reaction using ethyl/methyl acrylate in the presence of palladium catalyst.

Naturally Occurring Benzofuran: Isolation, Structure Elucidation and Total Synthesis of 5-(3-Hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-3-benzofurancarbaldehyde, a Novel Adenosine A1 Receptor Ligand Isolated from Salvia miltior

A naturally occurring benzofuran, namely 5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-3-benzofurancarbaldehyde was isolated from the roots of S. miltiorrhiza Bunge "Danshen".Its structure was established by means of spectroscopic metho