144790-81-8

Basic information

• Product Name: 2-(3-phenyl-1-propynyl)-3,4,4-trimethoxy-2-cyclobuten-1-one
• Synonyms: 2-(3-phenyl-1-propynyl)-3,4,4-trimethoxy-2-cyclobuten-1-one
• CAS NO: 144790-81-8
• Molecular Weight: 272.301
• Mol File: 144790-81-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-phenyl-1-propynyl)-3,4,4-trimethoxy-2-cyclobuten-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-phenyl-1-propynyl)-3,4,4-trimethoxy-2-cyclobuten-1-one(144790-81-8)
• EPA Substance Registry System: 2-(3-phenyl-1-propynyl)-3,4,4-trimethoxy-2-cyclobuten-1-one(144790-81-8)

Safety Data

• Hazardous Substances Data: 144790-81-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 113976-71-9 2,3-dimethoxy-4-hydroxy-4-(3-phenyl-1-propynyl)-2-cyclobuten-1-one 

Relevant articles and documents

A Potentially General Regiospecific Synthesis of Substituted Quinones from Dimethyl Squarate

A potentially general regiospecific synthesis of benzo- and naphthoquinones is described.This method starts with dimethyl squarate (1) which is converted to the cyclobutenone ketal 3 upon sequential treatment with an organolithium reagent and then BF3 etherate or TFAA in THF/methanol.Treatment of these with a second lithium reagent followed by hydrolysis gives the cyclobutenones 5.Addition of an alkynyl-, alkenyl- or aryllithium agent to 5 followed by hydrolysis of the ketal linkage gives the corresponding 4-alkynyl-, 4-alkenyl- or 4-aryl-4-hydroxycyclobutenones7 - 9, and these readily rearrange to the respective quinones or hydroquinones upon thermolysis in refluxing benzene.In a similar fashion, 15 was employed as a reagent to prepare mono- and disubstituted hydroquinones and quinones.