1447963-73-6

Basic information

• Product Name: Palladacycle Gen. 3
• Synonyms: Methanesulfonato(2-dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II), 98%;Methanesulfonato(2-dicyclohexylphosphino-2',6'-bis(dimethylamino)-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II),CPhos Palladacycle Gen. 3
• CAS NO: 1447963-73-6
• Molecular Formula: C41H54N3O3PPdS
• Molecular Weight: 806.35
• Product Categories: Buchwald Ligands&Precatalysts;Buchwald Precatalysts Series;Pd
• Mol File: 1447963-73-6.mol
• Article Data: 0

Chemical Properties

• Appearance: white to off-white/Powder
• CAS DataBase Reference: Palladacycle Gen. 3(CAS DataBase Reference)
• NIST Chemistry Reference: Palladacycle Gen. 3(1447963-73-6)
• EPA Substance Registry System: Palladacycle Gen. 3(1447963-73-6)

Safety Data

• Hazardous Substances Data: 1447963-73-6(Hazardous Substances Data)

Usage

Description

Palladacycle Gen. 3, also known as CPhos Pd G3, is a modified G3 precatalyst (G3′) synthesized by Buchwald and coworkers from the second generation (G2) precatalyst. It is obtained by methylation of the amino group present on the biphenyl backbone. Palladacycle Gen. 3 is a versatile catalyst that is useful for various cross-coupling reactions. It has a long life in solution and is readily soluble in various organic solvents, making it a promising candidate for a wide range of applications.

Uses

Used in Pharmaceutical Industry:
Palladacycle Gen. 3 is used as a catalyst for C-N bond forming reactions, which are crucial in the synthesis of various pharmaceutical compounds. Its ability to facilitate these reactions contributes to the development of new drugs and the improvement of existing ones.
Used in Chemical Synthesis:
In the field of chemical synthesis, Palladacycle Gen. 3 is used as a catalyst for various cross-coupling reactions. These reactions are essential for the formation of complex organic molecules, which are vital in the production of chemicals, dyes, and other materials.
Used in Research and Development:
Palladacycle Gen. 3 is employed as a catalyst in research and development laboratories, where it is used to study and optimize various cross-coupling reactions. Its long life in solution and solubility in various organic solvents make it an ideal candidate for exploring new reaction pathways and developing innovative synthetic methods.
Used in Environmental Applications:
Palladacycle Gen. 3 can be utilized in environmental applications, such as the degradation of pollutants and the synthesis of environmentally friendly materials. Its catalytic properties enable the development of more sustainable and eco-friendly processes in various industries.

Reactions

Catalyst for the highly selective cross-coupling of secondary alkylzinc reagents with heteroaryl halides Catalyst for the completely linear-selective Negishi cross-coupling of allylzinc halides with aryl and vinyl electrophiles