1450622-51-1Relevant articles and documents
Fe-promoted cross coupling of homobenzylic methyl ethers with Grignard reagents via sp3 C-O bond cleavage
Luo, Shuang,Yu, Da-Gang,Zhu, Ru-Yi,Wang, Xin,Wang, Lei,Shi, Zhang-Jie
, p. 7794 - 7796 (2013/09/02)
The first iron-catalyzed formal cross coupling of homobenzylic methyl ethers with alkyl Grignard reagents is realized. The reaction is proposed to proceed through a sequence of dehydroalkoxylation to form the vinyl-intermediate, followed by Fe-catalyzed selective carbometalation to form a benzylic Grignard reagent.