1450894-33-3

Basic information

• Product Name: ethyl 2-(2-(4-methoxybenzoyl)phenyl)acetate
• Synonyms: ethyl 2-(2-(4-methoxybenzoyl)phenyl)acetate
• CAS NO: 1450894-33-3
• Molecular Weight: 298.339
• Mol File: 1450894-33-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl 2-(2-(4-methoxybenzoyl)phenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(2-(4-methoxybenzoyl)phenyl)acetate(1450894-33-3)
• EPA Substance Registry System: ethyl 2-(2-(4-methoxybenzoyl)phenyl)acetate(1450894-33-3)

Safety Data

• Hazardous Substances Data: 1450894-33-3(Hazardous Substances Data)

Upstream product

• 129112-26-1 2-iodophenyltrifluoromethanesulfonic acid 
• 2881-83-6 ethyl 4-methoxybenzoylacetate 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 64-17-5 ethanol 
• 50439-04-8 [2-(4-methoxy-benzoyl)-phenyl]-acetic acid 

Relevant articles and documents

Cooperative Catalysis for the Highly Diastereo- and Enantioselective [4+3]-Cycloannulation of ortho-Quinone Methides and Carbonyl Ylides

We describe herein a highly diastereo- and enantioselective [4+3]-cycloannulation of ortho-quinone methides and carbonyl ylides to furnish functionalized oxa-bridged dibenzooxacines with excellent yields and stereoselectivity in a single synthetic step. The combination of rhodium and chiral phosphoric acid catalysis working in concert to generate both transient intermediates in situ provides direct access to complex bicyclic products with two quaternary and one tertiary stereogenic centers. The products may be further functionalized into valuable and enantiomerically highly enriched building blocks.

A novel and convenient strategy for the synthesis of phthalazines from an aryne precursor

A novel three-step entry toward phthalazine derivatives has been elaborated. A strategy based on a sequential acyl-alkylation/diazo transfer reaction/Diaza-Wittig reaction led to the desired analogues in moderate to good yields from an aryne precursor. Various aryl groups were introduced on the annulated pyridazine, moreover the presence of an ester group allows further modifications.