145100-51-2 Usage
Uses
Different sources of media describe the Uses of 145100-51-2 differently. You can refer to the following data:
1. 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine provides good yields of vinyl triflates from the corresponding ketone enolates or dienolates. It is used in the total synthesis of (-)-porantheridine and the trans decahydroquinoline alkaloid (+)-219A. It is also used as a reactant for Suzuki-Miyaura cross coupling, synthesis of nicotinic acetylcholine receptor-selective ligands, enantioselective desymmetrizing palladium catalyzed carbonylation reactions, synthesis of high affinity niacin receptor GPR109A agonists and in preparation of heteroaromatics.
2. Reactant for: Suzuki-Miyaura cross coupling Synthesis of nicotinic acetylcholine receptor-selective ligands Enantioselective desymmetrizing palladium catalyzed carbonylation reactions Synthesis of high affinity niacin receptor GPR109A agonists Preparation of heteroaromatics
Check Digit Verification of cas no
The CAS Registry Mumber 145100-51-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,1,0 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 145100-51:
(8*1)+(7*4)+(6*5)+(5*1)+(4*0)+(3*0)+(2*5)+(1*1)=82
82 % 10 = 2
So 145100-51-2 is a valid CAS Registry Number.
InChI:InChI=1/C8F8O2/c9-1-2(10)4(12)6(5(13)3(1)11)18-7(17)8(14,15)16
145100-51-2Relevant articles and documents
A metathesis-based approach to the synthesis of 2-pyridones and pyridines
Donohoe, Timothy J.,Fishlock, Lisa P.,Procopiou, Panayiotis A.
, p. 285 - 288 (2008/09/19)
(Chemical Equation Presented) The ring-closing metathesis reaction has been successfully employed to form a range of dihydropyridone intermediates, which are in the correct oxidation state to undergo a base-induced elimination to reveal the aromatic 2-pyridone. This mild and novel approach to six-membered heteroaromatic compounds then provides access to a wide variety of substituted pyridines in excellent overall yield.
Pyridine-derived triflating reagents: N-(2-pyridyl)-triflimide and n-(5-chloro-2-pyridyl)triflimide
Comins, Daniel L.,Dehghani, Ali,Foti, Christopher J.,Joseph, Sajan P.
, p. 77 - 77 (2017/09/08)
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