1452586-11-6

Basic information

• Product Name: 13-O-((2S,3R)-3-phenylglycidoyl)-7,10-O,O'-bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin
• CAS NO: 1452586-11-6
• Molecular Weight: 1041.54
• Mol File: 1452586-11-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 13-O-((2S,3R)-3-phenylglycidoyl)-7,10-O,O'-bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin(CAS DataBase Reference)
• NIST Chemistry Reference: 13-O-((2S,3R)-3-phenylglycidoyl)-7,10-O,O'-bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin(1452586-11-6)
• EPA Substance Registry System: 13-O-((2S,3R)-3-phenylglycidoyl)-7,10-O,O'-bis(2,2,2-trichloroethoxycarbonyl)-10-deacetylbaccatin(1452586-11-6)

Safety Data

• Hazardous Substances Data: 1452586-11-6(Hazardous Substances Data)

Upstream product

• 95603-44-4 7,10-di-(2,2,2-trichloroethyloxycarbonyl)-10-deacetylbaccatin III 
• 79898-17-2 (2S,3R)-β-phenylglycidic acid 

Relevant articles and documents

Regio- and stereoselective methods for the conversion of (2S,3R)-β-phenylglycidic acid esters to taxoids and other enantiopure (2R,3S)-phenylisoserine esters

A novel efficient method was proposed for the synthesis of enantiopure precursors of taxane-containing cytostatics, i.e., methyl esters of (2R,3S)- and (2S,3R)-N-benzoylphenylisoserine and similar taxoid esters. The method is based on the regio- and stereoselective hydrobromolysis of the corresponding trans-β-phenyl glycidate enatiomers, consecutive reactions of O-acylcarbamoylation of the obtained 3-bromohydrins, intramolecular cyclization to 4-phenyloxazolidin-2-one-5-carboxylic acid derivatives, and oxazolidinone ring opening.