145572-44-7 Usage
Description
A tetracyclic alkaloid present in Sophora species, this base crystallizes from H20
as the monohydrate, m.p. 54-5°C which becomes anhydrous in vacuo. It has
[α]18D - 29.44° (EtOH) and yields the following salts: hydrochloride, m.p. >
300°C; hydriodide, m.p. 277-9°C; aurichloride, m.p. l66-7°C; platinichloride,
m.p. 207-212°C (dec.); picrate, m.p. ISS-7°C and the methiodide, m.p. 200-2°C. Reduction of the base by electrolysis yields a crystalline, volatile base,
ClsH26N2, b.p. l53-4°C/5 mm; [α]D - 26.2° (EtOH) and giving a methiodide
with a melting point above 300°C. Attempted degradation by the Hofmann
process has proved unsuccessful.
Uses
Sophocarpine Monohydrate alleviates non-alcoholic steatohepatitis, which is a resultant effect of non-alcoholic fatty lifer disease. Admission of this compound results in a decrease in liver weight and serum lipids. Antiviral agent, Sophocarpine also displays a profound effect against coxsackievirus and therapeutical effects of viral myocarditis.
References
Orekhov, Proskurnina., Ber., 67,77 (1934)
Proskurnina, Kuzuvkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962)
Check Digit Verification of cas no
The CAS Registry Mumber 145572-44-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,5,7 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 145572-44:
(8*1)+(7*4)+(6*5)+(5*5)+(4*7)+(3*2)+(2*4)+(1*4)=137
137 % 10 = 7
So 145572-44-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h1,7,11-13,15H,2-6,8-10H2
