14580-10-0

Basic information

• Product Name: 1-(2-Chloro-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one
• Synonyms: 1-(2-Chloro-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one
• CAS NO: 14580-10-0
• Molecular Formula: C10H9ClN2O
• Molecular Weight: 208.64426
• Mol File: 14580-10-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-Chloro-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Chloro-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one(14580-10-0)
• EPA Substance Registry System: 1-(2-Chloro-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one(14580-10-0)

Safety Data

• Hazardous Substances Data: 14580-10-0(Hazardous Substances Data)

Usage

Description

1-(2-Chloro-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one, commonly known as Clotrimazole, is a versatile antifungal medication that belongs to the azole class of drugs. It is characterized by its ability to effectively treat a range of fungal infections by disrupting the cell membranes of fungi, leading to their destruction.

Uses

Used in Pharmaceutical Industry:
Clotrimazole is used as an antifungal agent for treating various fungal infections such as athlete's foot, ringworm, jock itch, and vaginal yeast infections. Its application is based on its ability to disrupt the cell membranes of fungi, causing their death and providing relief from the symptoms of the infection.
Used in Topical Medications:
Clotrimazole is used as an active ingredient in various forms of topical medications, including creams, powders, and solutions. These formulations are applied directly to the affected area to provide targeted treatment and relief from fungal infections.
Used in Oral Health:
Clotrimazole is also used in the form of oral lozenges for the treatment of oral thrush, a fungal infection that affects the mouth and throat. Its application in this context is due to its effectiveness in eradicating the fungus responsible for the infection and alleviating the associated symptoms.
Overall, 1-(2-Chloro-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one, or Clotrimazole, is a widely recognized and utilized antifungal agent in the pharmaceutical industry, providing effective treatment for a variety of fungal infections when used as directed. However, it is important to note that it may cause mild irritation or allergic reactions in some individuals, and its safety and efficacy are generally considered to be high.

Relevant articles and documents

Studies on fungicides. 18. Synthesis and antifungal activity of halogen substituted phenylhydrazine derivatives and related compounds

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