14585-04-7

Basic information

• Product Name: 5,7-DIHYDROXY-3,3',4',5'-TETRAMETHOXYFLAVONE
• Synonyms: 5,7-DIHYDROXY-3,3',4',5'-TETRAMETHOXYFLAVONE;MYRICETIN 3,3',4',5'-TETRAMETHYL ETHER;3,3',4',5'-Tetramethylmyricetin
• CAS NO: 14585-04-7
• Molecular Formula: C₁₉H₁₈O₈
• Molecular Weight: 374.34142
• Product Categories: Tetra-substituted Flavones
• Mol File: 14585-04-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 594.2°Cat760mmHg
• Flash Point: 214.3°C
• Appearance: /
• Density: 1.44g/cm³
• PKA: 6.29±0.40(Predicted)
• CAS DataBase Reference: 5,7-DIHYDROXY-3,3',4',5'-TETRAMETHOXYFLAVONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-DIHYDROXY-3,3',4',5'-TETRAMETHOXYFLAVONE(14585-04-7)
• EPA Substance Registry System: 5,7-DIHYDROXY-3,3',4',5'-TETRAMETHOXYFLAVONE(14585-04-7)

Safety Data

• Hazardous Substances Data: 14585-04-7(Hazardous Substances Data)

Upstream product

• 55317-02-7 2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone 
• 1719-88-6 3,4,5-trimethoxybenzoic anhydride 
• 108-73-6 3,5-dihydroxyphenol 
• 118-41-2 Eudesmic acid 

Downstream Products

• 529-44-2 myricetin 
• 54614-59-4 5-hydroxy-3-methoxy-7-(toluene-4-sulfonyloxy)-2-(3,4,5-trimethoxy-phenyl)-chromen-4-one 

Relevant articles and documents

Myricitrin preparation method

The invention belongs to the technical field of pharmaceutical chemical synthesis, in particular relates to a preparation method of the slots. The invention the equivalent preparation method is as follows: a, in order to 1 - 1 as shown in the compound as a raw material, with the methoxy second grade nitrile under acidic conditions in the acylation reaction to obtain 1 - 3 as shown in the; second, 1 - 3 is shown with the compound 3, 4, 5 - trimethoxy benzoic anhydride generating rearrangement reaction to 1 - 5 as shown in the; three, 1 - 5 shown BBr3 compound in the dichloromethane solution takes place in the demethylation reaction generating 3 - 1 compound of formula, is myricetin. The invention relates to a fully synthetic routes proceed from the phloroglucinol, by the three-step reaction, to 60% of the total yield has succeeded in synthesizing myricetin. With cheap raw material, mild reaction conditions, synthetic route is short, and the yield is high, the operation is simple, and little environmental pollution and the like.