1462-82-4

Basic information

• Product Name: 2-acetamido-N,N-bis(2-chloroethyl)-3-phenyl-propanamide
• Synonyms: 2-acetamido-N,N-bis(2-chloroethyl)-3-phenyl-propanamide
• CAS NO: 1462-82-4
• Molecular Formula: C₁₅H₂₀Cl₂N₂O₂
• Molecular Weight: 0
• Mol File: 1462-82-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 549°Cat760mmHg
• Flash Point: 285.8°C
• Appearance: /
• Density: 1.221g/cm³
• Vapor Pressure: 4.21E-12mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: 2-acetamido-N,N-bis(2-chloroethyl)-3-phenyl-propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetamido-N,N-bis(2-chloroethyl)-3-phenyl-propanamide(1462-82-4)
• EPA Substance Registry System: 2-acetamido-N,N-bis(2-chloroethyl)-3-phenyl-propanamide(1462-82-4)

Safety Data

• Hazardous Substances Data: 1462-82-4(Hazardous Substances Data)

Usage

Type of compound

Nitrogen mustard alkylating agent

Use

Treatment of certain types of cancer (e.g. chronic lymphocytic leukemia, Hodgkin's disease, non-Hodgkin's lymphoma)

Mechanism of action

Attaches to DNA of cancer cells, preventing them from dividing and growing

Properties

Cytotoxic and mutagenic

Administration

Orally or through injection

Side effects

Bone marrow suppression, nausea, increased risk of infection and bleeding

Caution

Potential for damage to healthy cells, should only be used under supervision of a qualified healthcare professional.

InChI:InChI=1/C15H20Cl2N2O2/c1-12(20)18-14(11-13-5-3-2-4-6-13)15(21)19(9-7-16)10-8-17/h2-6,14H,7-11H2,1H3,(H,18,20)

Upstream product

• 2901-75-9 (R,S)-N-acetyl phenylalanine 
• 334-22-5 N,N-bis(chloro-2-ethyl)amine