146305-31-9

Basic information

• Product Name: C₁₇H₁₈N₄O₂S
• CAS NO: 146305-31-9
• Molecular Weight: 342.422
• Mol File: 146305-31-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₈N₄O₂S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₈N₄O₂S(146305-31-9)
• EPA Substance Registry System: C₁₇H₁₈N₄O₂S(146305-31-9)

Safety Data

• Hazardous Substances Data: 146305-31-9(Hazardous Substances Data)

Upstream product

• 542-85-8 Ethyl isothiocyanate 
• 146305-29-5 N-[4-(hydrazinylcarbonyl)phenyl]benzamide 
• 94-09-7 p-aminoethylbenzoate 
• 98-88-4 benzoyl chloride 
• 736-40-3 N-benzoylbenzocaine 

Downstream Products

• 29527-37-5 5-(4-aminophenyl)-2,4-dihydro-4-ethyl-3H-1,2,4-triazole-3-thione 

Relevant articles and documents

Some 3-Thioxo/Alkylthio-1,2,4-triazoles with a Substituted Thiourea Moiety as Possible Antimycobacterials

A series of novel N-alkyl/aryl-N'-[4-(4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thione-5-yl)phenyl]thioureas 1-19 and three S-alkylated representatives of the former, N-alkyl/aryl-N'-[4-(3-aralkylthio-4-alkyl/aryl-4H-1,2,4-triazole-5-yl)phenyl]thioureas 20-22, were synthesized and tested for antimycobacterial activity against Mycobacterium tuberculosis H37Rv as well as Mycobacterium fortuitum ATCC 6841 which is a rapid growing opportunistic pathogen. Compounds 4 and 9-11 were found to possess the same MIC value with that of Tobramycin against M. fortuitum ATCC 6841 whereas 1-3 and 21 had positive response against M. tuberculosis H37Rv at varying degrees. Compound 21 was identified as the most potent derivative of the 1-22 series by an MIC value of 6.25 μg/ml and selectivity index of 1.6