146467-21-2 Usage
Description
(2S)-5-Oxo-piperidine-2-carboxylic acid is a piperidine derivative with the molecular formula C6H9NO3, featuring a carboxylic acid group and a keto group. It has a molecular weight of 143.14 g/mol and a chiral center at the second position, making it a key intermediate in the synthesis of pharmaceutical compounds and a building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
(2S)-5-Oxo-piperidine-2-carboxylic acid is used as a key intermediate for the synthesis of various pharmaceutical compounds due to its unique chemical structure and reactivity.
Used in Organic Synthesis:
(2S)-5-Oxo-piperidine-2-carboxylic acid is used as a building block in organic synthesis, enabling the development of new compounds and reactions.
Used in Drug Development:
(2S)-5-Oxo-piperidine-2-carboxylic acid is used in the development of drugs and medicines, taking advantage of its stereochemistry and potential for stereoselective reactions and asymmetric synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 146467-21-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,4,6 and 7 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 146467-21:
(8*1)+(7*4)+(6*6)+(5*4)+(4*6)+(3*7)+(2*2)+(1*1)=142
142 % 10 = 2
So 146467-21-2 is a valid CAS Registry Number.
146467-21-2Relevant articles and documents
Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof
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Page/Page column 25, (2021/10/13)
The present application relates to methods of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or its derivatives in an environment-friendly way. The method uses L-glutamic acid as a starting material, which is first subjected to esterification reaction in the presence of an acidic reagent, and then reacted successively with 2-haloacetate and N-protecting agent, or with N-protecting agent and 2-haloacetate under a basic condition to obtain compound IV; then, the obtained compound IV is subjected to intramolecular condensation into a ring under the action of a strong base to obtain N-protecting group piperidine-5-one-2S-carboxylate (V).
