146500-63-2

Basic information

• Product Name: Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-
• CAS NO: 146500-63-2
• Molecular Formula: C9H4BrF5
• Molecular Weight: 287.027
• Mol File: 146500-63-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-(146500-63-2)
• EPA Substance Registry System: Benzene, 1-bromo-4-[2,2-difluoro-1-(trifluoromethyl)ethenyl]-(146500-63-2)

Safety Data

• Hazardous Substances Data: 146500-63-2(Hazardous Substances Data)

Upstream product

• 431-66-3 2-iodo-1,1,3,3,3-pentafluoropropene 
• 589-87-7 1,4-bromoiodobenzene 
• 301664-42-6 1-(tert-butyldimethylsilyl)-prop-2-yn-1-ol 
• 53243-15-5 2-ethynyl-1H-benzo[d]imidazole 
• 16184-89-7 4'-bromo-2,2,2-trifluoroacetophenone 
• 1895-39-2 sodium chlorodifluoroacetate 

Downstream Products

• 61587-27-7 p-(F-2-Propenyl)benzoesaeure 
• 2396-23-8 1-bromo-4-(perfluoropropan-2-yl)benzene 

Relevant articles and documents

An I(I)/I(III) Catalysis Route to the Heptafluoroisopropyl Group: A Privileged Module in Contemporary Agrochemistry

The heptafluoroisopropyl group is emerging as a privileged chemotype in contemporary agrochemistry and features prominently in the current portfolio of leading insecticides. To reconcile the expansive potential of this module with the synthetic challenges

Preparation of β,β-Difluoro-α-(trifluoromethyl)styrenes by Palladium-Catalyzed Coupling of Aryl Iodides with Pentafluoropropen-2-ylzinc Reagent

Substituted aromatic iodides are functionalized by pentafluoropropen-2-ylzinc, CF3C(ZnX)=CF2 (X = Br, I, or CF2=CCF3-), in the presence of Pd(PPh3)4 to give the corresponding arenes in good yields.This is particularly attractive for the preparation of title styrenes substituted with groups such as -NO2 or CO2R, which are incompatible with organomagnesium reagents.The best yields of the title styrenes with electron-donating substituents were obtained in DMF.For electron-withdrawing substituents, the best results were achieved in triglyme.A correlation was observed between Hammett ? constants and 19F NMR chemical shifts (R = 0.93-0.99, n = 8) and 2JF-F coupling constants (R = 0.94, n = 8).