1470-50-4

Basic information

• Product Name: TRANS-2-OCTENOIC ACID
• Synonyms: (2E)-2-Octenoic acid;2-OCTENOIC ACID (TRANS-);2-OCTENOIC ACID;FEMA NUMBER 3957;T2 OCTENOIC ACID;RARECHEM AL BK 0164;TRANS-2-OCTENOIC ACID;2-Octenoic acid oct-2-enoic acid
• CAS NO: 1470-50-4
• Molecular Formula: C₈H₁₄O₂
• Molecular Weight: 142.2
• EINECS: 216-001-6
• Mol File: 1470-50-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 5-6 °C(lit.)
• Boiling Point: 154 °C22 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.944 g/mL at 25 °C(lit.)
• Vapor Pressure: 5.07E-11mmHg at 25°C
• Refractive Index: n20/D 1.4588(lit.)
• CAS DataBase Reference: TRANS-2-OCTENOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-2-OCTENOIC ACID(1470-50-4)
• EPA Substance Registry System: TRANS-2-OCTENOIC ACID(1470-50-4)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-28-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 1470-50-4(Hazardous Substances Data)

Usage

General Description

TRANS-2-OCTENOIC ACID, also known as (E)-2-octenoic acid, is a naturally occurring unsaturated fatty acid. It is classified as a medium-chain fatty acid and is commonly found in various food sources, including butter, cheese, and beer. TRANS-2-OCTENOIC ACID has a slightly sweet, fruity, and fatty odor and is often used as a flavoring agent in food products. It is also used in the production of various fragrances and as a precursor for the synthesis of other organic compounds. Additionally, TRANS-2-OCTENOIC ACID has been studied for its potential pharmaceutical and antimicrobial properties, with research showing promising results for its use in treating certain medical conditions.

InChI:InChI=1/C14H26O5/c15-12(11-14(18)19)9-7-5-3-1-2-4-6-8-10-13(16)17/h12,15H,1-11H2,(H,16,17)(H,18,19)

Upstream product

• 5663-96-7 oct-2-ynoic acid 
• 141-82-2 malonic acid 
• 66-25-1 hexanal 
• 71-41-0 pentan-1-ol 
• 110-62-3 pentanal 
• 79-08-3 bromoacetic acid 
• 5163-67-7 (E)-oct-3-enoic acid 
• 4071-85-6 trimetylsilylketene 

Downstream Products

• 2351-90-8 Ethyl oct-2-enoate 
• 95770-49-3 2--phenol 

Relevant articles and documents

Mining the Cinnabaramide Biosynthetic Pathway to Generate Novel Proteasome Inhibitors

The cinnabaramides and salinosporamides are mixed PKS/NRPS natural products isolated from a terrestrial streptomycete and a marine actinomycete, respectively. They interfere with the proteasome and thus potentially inhibit the growth of cancer cells. The compounds exhibit a γ-lactam-β-lactone bicyclic ring structure attached to a cyclohexenyl unit and a PKS side chain. As a first step towards improving anticancer activity and permitting genetic approaches to novel analogues, we have cloned and characterized the cinnabaramide biosynthetic genes from Streptomyces sp. JS360. In addition to the expected PKS and NRPS genes, the cluster encodes functionalities for the assembly of the hexyl side chain precursor. The corresponding enzymes exhibit relaxed substrate specificities towards a number of synthesized precursors, enabling production of novel chlorinated cinnabaramides. These were isolated and analyzed for activity, revealing that derivatives bearing a chlorine atom in the PKS side chain show higher inhibitory potentials towards the proteasome's proteolytic subunits (especially the trypsin and chymotrypsin units) and higher cytotoxicities towards human tumor cell lines than the parent cinnabaramide A. Although their activities towards the proteasome were weaker than that of salinosporamide A, the cinnabaramides were found to inhibit the growth of various fungi with greater potency. Copyright

Alpha, beta-unsaturated carbonyl compound production method

The present invention relates to an alpha, beta-unsaturated carbonyl compound production method comprising the following steps: (1) oxidizing reaction of a primary alcohol with 3-20 carbon atoms under the effect of an oxidase for selective oxidation of a terminal alcoholic hydroxyl group into an aldehyde group to obtain an aldehyde group compound; (2) Reformatsky reaction of the aldehyde group compound and a halide under the catalytic effect of a metal to produce a corresponding alpha, beta-unsaturated carbonyl compound, the alpha, beta-unsaturated carbonyl compound production method is low-cost, less in environmental pollution, moreover, by alcohol oxidizing reaction by use of the oxidase, the quantitative and high selectivity corresponding alpha, beta-unsaturated carbonyl compound can be obtained, and the after processing is convenient.

Selective heterogeneous palladium-catalyzed hydrogenations of watersoluble alkenes and alkynes

Treatment of water-soluble alkenes or alkynes with palladium(II) acetate and triethoxysilane at room temperature afforded the corresponding hydrogenated products in high yields. Simple introduction of a stoichiometric amount of hydrogen is accomplished by using triethoxysilane as the hydrogen source.