14719-31-4

Basic information

• Product Name: N-(2,3-dimethylphenyl)-2,2,2-trifluoroacetamide
• Synonyms: acetamide, N-(2,3-dimethylphenyl)-2,2,2-trifluoro-
• CAS NO: 14719-31-4
• Molecular Formula: C₁₀H₁₀F₃NO
• Molecular Weight: 217.1877
• Mol File: 14719-31-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 253.6°C at 760 mmHg
• Flash Point: 107.2°C
• Density: 1.266g/cm³
• Vapor Pressure: 0.0181mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: N-(2,3-dimethylphenyl)-2,2,2-trifluoroacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,3-dimethylphenyl)-2,2,2-trifluoroacetamide(14719-31-4)
• EPA Substance Registry System: N-(2,3-dimethylphenyl)-2,2,2-trifluoroacetamide(14719-31-4)

Safety Data

• Hazardous Substances Data: 14719-31-4(Hazardous Substances Data)

Upstream product

• 87-59-2 2,3-Dimethylaniline 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 183180-26-9 N-methyl-N-(2,3-dimethylphenyl)-2-(3-{N-[2-(N-tert-butoxycarbonylamino)acetyl]-N-(N-methyl-N-phenylcarbamoylmethyl)amino}phenoxy)acetamide 
• 183180-25-8 N-Methyl-N-(2,3-dimethylphenyl)-2-[3-[N-(2-aminoacetyl)-N-(N-methyl-N-phenylcarbamoylmethyl)amino]phenoxy]acetamide 
• 184870-83-5 N-Methyl-N-(2,3-dimethylphenyl)-2-bromoacetamide 
• 41456-51-3 N-methyl-2,3-dimethylaniline 

Relevant articles and documents

Carbon-Carbon Bond Formation of Trifluoroacetyl Amides with Grignard Reagents via C(O)-CF3 Bond Cleavage

The reaction of trifluoroacetyl amides with Grignard reagent for the substitution of CF3 group with various alkyl or aryl groups is described. A variety of aryl, quinolin-8-yl, and (hetero)alkyl functional groups as well as F, Cl, and Br atoms are well tolerated. These moisture-stable and easily available trifluoroacetyl amides can be conveniently obtained and used as new versatile precursors for isocyanates. The control experiments show that the reaction proceeds via an isocyanate intermediate and/or alkoxide/amide dual anionic intermediate.

DIHYDROBENZOFURAN DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS

A compound represented by the formula (I): or a salt thereof exhibits excellent inhibitory activity of lipid peroxidation and is useful as an agent for inhibiting lipoperoxide production, wherein A ring denotes a non-aromatic 5- to 7-membered nitrogen-con