1472-75-9 Usage
General Description
The chemical "(5α,13β,19α)-1,2-Didehydro-3β-methoxycrinan-11-one" is a member of the crinanone alkaloid family and is found in certain plant species. It is a didehydro derivative of crinanone, with a methoxy group at the 3β position. (5α,13β,19α)-1,2-Didehydro-3β-methoxycrinan-11-one has a unique molecular structure, consisting of a tetracyclic ring system with a lactone ring. Research on this chemical has shown potential pharmacological properties, including antitumor and cytotoxic effects. Further studies are needed to fully understand its biological activities and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1472-75-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,7 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1472-75:
(6*1)+(5*4)+(4*7)+(3*2)+(2*7)+(1*5)=79
79 % 10 = 9
So 1472-75-9 is a valid CAS Registry Number.
1472-75-9Relevant articles and documents
Synthesis and antimalarial activity of new haemanthamine-type derivatives
Cedron, Juan C.,Gutierrez, David,Flores, Ninoska,Ravelo, Angel G.,Estevez-Braun, Ana
, p. 5464 - 5472 (2012/10/30)
Thirty one derivatives were prepared from the natural alkaloids haemanthamine (1), haemanthidine (2) and 11-hydroxyvittatine (3). They were evaluated for their in vitro antimalarial activity against chloroquine-sensitive strains of Plasmodium falciparum and some structure-activity relationships were outlined. For haemanthamine derivatives having a methoxy group at C-3, the presence of a free hydroxyl group at C-11 is important for the activity. The double bond at C-1-C-2 plays also an important role to achieve good inhibitory activity. Compound 35 with two nicotinate groups at C-3 and at C-11 was the most active compound with a IC50 = 0.8 ± 0.06 μM.
