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147359-76-0

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147359-76-0 Usage

Description

Flibanserin Hydrochloride is a pharmaceutical compound that acts as a 5-HT1A agonist and a 5-HT2A antagonist. It is primarily developed for the treatment of hypoactive sexual desire disorder in women, a condition characterized by a persistent or recurring deficiency in sexual fantasies and desire for sexual activity.

Uses

Used in Pharmaceutical Industry:
Flibanserin Hydrochloride is used as a therapeutic agent for the treatment of hypoactive sexual desire disorder (HSDD) in women. It works by modulating the levels of serotonin in the brain, which is believed to influence sexual desire and arousal. The compound's dual action as a 5-HT1A agonist and 5-HT2A antagonist helps to increase sexual desire and satisfaction in women suffering from HSDD.
In addition to its primary application, Flibanserin Hydrochloride may also have potential uses in other areas of medicine, such as the treatment of sexual dysfunction in men or other conditions related to serotonin regulation. However, further research and clinical trials would be necessary to establish its efficacy and safety in these contexts.

Check Digit Verification of cas no

The CAS Registry Mumber 147359-76-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,3,5 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 147359-76:
(8*1)+(7*4)+(6*7)+(5*3)+(4*5)+(3*9)+(2*7)+(1*6)=160
160 % 10 = 0
So 147359-76-0 is a valid CAS Registry Number.

147359-76-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Flibanserin Hydrochloride

1.2 Other means of identification

Product number -
Other names Flibanserin HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147359-76-0 SDS

147359-76-0Downstream Products

147359-76-0Relevant articles and documents

A Facile Route of Synthesis for Making Flibanserin

Yang, Feipu,Wu, Chunhui,Li, Zhiqiang,Tian, Guanghui,Wu, Jianzhong,Zhu, Fuqiang,Zhang, Jian,He, Yang,Shen, Jingshan

, p. 1576 - 1580 (2016)

A novel and efficient route of synthesis for making flibanserin via 2-ethoxy-1H-benzo[d]imidazole (12) was described with excellent yield. This protocol provided a more facile approach to flibanserin.

A preparation method of flibanserin (by machine translation)

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Paragraph 0064; 0065; 0068, (2017/07/21)

The invention discloses a method for preparing of flibanserin, includes the steps of: (1) compound I with dichloroethane reaction to obtain compound II, its without purification, directly with compound III reaction, to obtain the compound IV; (2) compound

NOVEL POLYMORPHS OF FLIBANSERIN HYDROCHLORIDE

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Page/Page column 17, (2010/12/31)

The present invention provides novel crystalline anhydrous form II, hemihydrate form III, anhydrous form IV, anhydrous form V, anhydrous form VI, hemihydrate form VII, hemihydrate form VIII, hemihydrate form IX and amorphous form of flibanserin hydrochloride, processes for its preparation and to pharmaceutical compositions containing them.

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