147751-16-4

Basic information

• Product Name: Carbamic acid, (methylsulfonyl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (methylsulfonyl)-, 1,1-dimethylethyl ester (9CI);Carbamic acid, (methylsulfonyl)-, 1,1-dimethylethyl ester;(Methylsulfonyl)carbamic acid 1,1-dimethylethyl ester;tert-Butyl N-methanesulfonylcarbamate;tert-Butyl MethylsulfonylcarbaMate
• CAS NO: 147751-16-4
• Molecular Formula: C₆H₁₃NO₄S
• Molecular Weight: 195.23672
• Product Categories: N-BOC
• Mol File: 147751-16-4.mol
• Article Data: 21

Chemical Properties

• Melting Point: 108-109 °C
• Appearance: White to off-white powder
• Density: 1.213 g/cm³
• Refractive Index: 1.461
• Storage Temp.: 2-8°C
• PKA: 4.56±0.40(Predicted)
• CAS DataBase Reference: Carbamic acid, (methylsulfonyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (methylsulfonyl)-, 1,1-dimethylethyl ester (9CI)(147751-16-4)
• EPA Substance Registry System: Carbamic acid, (methylsulfonyl)-, 1,1-dimethylethyl ester (9CI)(147751-16-4)

Safety Data

• Hazardous Substances Data: 147751-16-4(Hazardous Substances Data)

Usage

General Description

Carbamic acid, (methylsulfonyl)-, 1,1-dimethylethyl ester (9CI) is a chemical compound that is commonly used as a pesticide and herbicide in agriculture. It is also known by its chemical formula C7H15NO3S. Carbamic acid, (methylsulfonyl)-, 1,1-dimethylethyl ester (9CI) is a colorless, odorless liquid that is soluble in water and has a low volatility. It is considered to be relatively stable under normal conditions, but it can react with strong acids, bases, and oxidizing agents. The primary use of this chemical is as a pesticide to control a wide range of pests, including insects, mites, and fungi. It is important to handle and use this chemical with caution, following all safety guidelines and regulations.

InChI:InChI=1/C6H13NO4S/c1-6(2,3)11-5(8)7-12(4,9)10/h1-4H3,(H,7,8)

Upstream product

• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 3144-09-0 methanesulfonamide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1122-58-3 dmap 
• 121-44-8 triethylamine 

Downstream Products

• 410529-86-1 tert-butyl(((diphenylphosphoryl)methyl)sulfonyl)carbamate 
• 914801-93-7 N-tert-butoxycarbonyl-2-(2-(methoxymethyloxy)phenyl)-2-oxo-ethylsulfonamide 
• 1002761-80-9 N-tert-butyl ester-N-(4-benzylsulfanyl-5-nitro-thiophen-3-ylmethyl)-methanesulfonamide 
• 942066-43-5 tert-butyl N-[(3-hydroxy-4-(benzyloxy)butyl)sulfonyl]carbamate 
• 942066-38-8 tert-butyl N-[(3-hydroxy-4-phenoxybutyl)sulfonyl]carbamate 
• 942066-40-2 tert-butyl N-[(3-hydroxy-4-(4-methylphenoxy)butyl)sulfonyl]carbamate 
• 942066-41-3 tert-butyl N-[(3-hydroxy-4-(2-methylphenoxy)butyl)sulfonyl]carbamate 
• 942066-39-9 tert-butyl N-[(3-hydroxy-4-(4-(trifluoromethyl)phenoxy)butyl)sulfonyl]carbamate 
• 914801-94-8 5'-amino-5'-N,N⁶-di-tert-butoxycarbonyl-5'-deoxy-2',3'-O-isopropylidene-5'-N-[(2-(2-(methoxymethyloxy)phenyl)-2-oxo-ethyl)sulfonyl]adenosine 
• 914801-95-9 5'-amino-5'-N,N⁶-di-tert-butoxycarbonyl-5'-deoxy-2',3'-O-isopropylidene-5'-N-[(1,1-difluoro-2-(2-(methoxymethyloxy)phenyl)-2-oxo-ethyl)sulfonyl]adenosine 
• 1028072-66-3 tert-butyl N-(E)-styrylsulfonylcarbamate 
• 1026822-40-1 C₁₃H₁₆ClNO₄S 

Relevant articles and documents

Facile Preparation of N-(sulfonyl)carbamates

N-(Sulfonyl)carbamates, useful N-nucleophiles in the Mitsunobu reaction, can be prepared readily by reaction of sulfonamides with chloroformates (or dicarbonates) catalyzed by 4-(dimethylamino)pyridine.

Identification of a novel orally bioavailable NLRP3 inflammasome inhibitor

NLRP3 inflammasome mediated release of interleukin-1β (IL-1β) has been implicated in various diseases, including COVID-19. In this study, rationally designed alkenyl sulfonylurea derivatives were identified as novel, potent and orally bioavailable NLRP3 i

An unconventional sulfur-to-selenium-to-carbon radical transfer: Chemo-and regioselective cyclization of yne-ynamides

An uncommon sulfur → selenium → carbon radical transfer process is employed to develop an unprecedented selenyl radical-mediated regioselective cyclization of yne-tethered-ynamides. Density functional theory studies and HRMS experiments are used to establish a reactivity scale between thiyl and selenyl radicals. The unique features of this transformation include, (1) the chemoselective reactivity of RSe over RS, (2) regioselective RSe attack on alkyne over ynamide, (3) 5-exo-dig cyclization of yne-ynamide to unusual 4-selenyl-pyrroles, and (4) the green synthetic method. The reaction of methyldiselenide with yne-ynamides to methylselenopyrroles is also described.

HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS

The invention relates to activators of FXR useful in the treatment of autoimmune disorders, liver disease, intestinal disease, kidney disease, cancer, and other diseases in which FXR plays a role, having the Formula (I): (I), wherein L1, A, X1, X2, R1, R2, and R3 are described herein.