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148433-01-6

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148433-01-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 148433-01-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,4,3 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 148433-01:
(8*1)+(7*4)+(6*8)+(5*4)+(4*3)+(3*3)+(2*0)+(1*1)=126
126 % 10 = 6
So 148433-01-6 is a valid CAS Registry Number.

148433-01-6Downstream Products

148433-01-6Relevant articles and documents

Formal total synthesis of aliskiren

Peters, Byron K.,Liu, Jianguo,Margarita, Cristiana,Andersson, Pher G.

, p. 7292 - 7296 (2015)

The efficient and selective formal total synthesis of aliskiren is described. Aliskiren, a renin inhibitor drug, has received considerable attention, primarily because it is the first of the renin inhibitor drugs to be approved by the FDA. Herein, the formal synthesis of aliskiren by iridium-catalyzed asymmetric hydrogenation of two allylic alcohol fragments is reported. Screening a number of N,P-ligated iridium catalysts yielded two catalysts that gave the highest enantioselectivity in the hydrogenation, which gave the saturated alcohols in 97 and 93 % ee. In only four steps after hydrogenation, the fragments were combined by using the Julia-Kocienski reaction to produce late-stage intermediate in an overall yield of 18 %.

Synthesis and anticancer activity of chalcone-pyrrolobenzodiazepine conjugates linked via 1,2,3-triazole ring side-armed with alkane spacers

Kamal, Ahmed,Prabhakar,Janaki Ramaiah,Venkat Reddy,Ratna Reddy, Ch.,Mallareddy,Shankaraiah, Nagula,Lakshmi Narayan Reddy,Pushpavalli,Pal-Bhadra, Manika

experimental part, p. 3820 - 3831 (2011/11/12)

Aiming to develop multitarget drugs for the anticancer treatment, a new class of chalcone-pyrrolo[2,1-c] [1,4]benzodiazepine (PBD) conjugates linked through a 1,2,3-triazole moiety containing alkane spacers has been designed and synthesized. Combining the

Radical isomerization via intramolecular ipso substitution of aryl ethers: Aryl translocation from oxygen to carbon

Lee, Eun,Lee, Chulbom,Tae, Jin Sung,Whang, Ho Sung,Li, Kap Sok

, p. 2343 - 2346 (2007/10/02)

Bromopropyl aryl ethers an converted to 3-arylpropanols under standard radical generating conditions in the presence of tributylstannane and AIBN. This rearrangement involves intramolecular ipso attack of the alkyl radicals which generates spiro cyclohexadienyl radical intermediates.

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