148905-81-1

Basic information

• Product Name: (-)-(4AR)-(10BR)-8-chloro-4-(S-α-methylbenzyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-3-one
• CAS NO: 148905-81-1
• Molecular Weight: 339.865
• Mol File: 148905-81-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-(4AR)-(10BR)-8-chloro-4-(S-α-methylbenzyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(4AR)-(10BR)-8-chloro-4-(S-α-methylbenzyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-3-one(148905-81-1)
• EPA Substance Registry System: (-)-(4AR)-(10BR)-8-chloro-4-(S-α-methylbenzyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-3-one(148905-81-1)

Safety Data

• Hazardous Substances Data: 148905-81-1(Hazardous Substances Data)

Upstream product

• 148835-23-8 (6-Chloro-3,4-dihydro-naphthalen-2-yl)-((S)-1-phenyl-ethyl)-amine 
• 17556-18-2 6-chloro-3,4-dihydro-1H-naphthalen-2-one 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 148835-22-7 8-Chloro-4-((S)-1-phenyl-ethyl)-1,4,5,6-tetrahydro-2H-benzo[f]quinolin-3-one 

Downstream Products

• 146117-78-4 bexlosteride 

Relevant articles and documents

Synthesis of the individual enantiomers of the benzoquinolinone human type 1 steroid 5-α-reductase inhibitors LY191704 and LY266111

The first syntheses of the individual enantiomers of the benzoquinolinone class of selective inhibitors of human Type 1 steroid 5-α-reductase are described. For benzoquinolinones lacking an angular substituent, the approach relies upon an enamine acryloyl