148990-17-4 Usage
Description
4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyrimidine is a pyrimidine derivative with a molecular formula C13H12N2OS. It features a methylsulfanyl group attached to the second carbon atom and a 4-methoxyphenyl group attached to the fourth carbon atom. 4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyriMidine possesses unique steric and electronic properties due to the presence of these functional groups, making it a promising candidate for pharmaceutical applications and organic synthesis.
Uses
Used in Pharmaceutical Applications:
4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyrimidine is used as a ligand for various biological targets such as enzymes and receptors. Its unique structure allows it to interact with these targets, potentially leading to the development of new drugs for treating various diseases.
Used in Organic Synthesis:
4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyrimidine serves as a building block in organic synthesis, enabling the creation of more complex molecules with diverse applications. Its versatile structure can be further modified to generate a range of novel compounds with potential uses in various industries.
Used in Medicinal Chemistry Research:
The presence of the methoxyphenyl and methylsulfanyl groups in 4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyrimidine provides it with unique steric and electronic properties. These properties can be exploited for medicinal chemistry research, allowing scientists to explore its potential as a lead compound for drug discovery and development.
Used in Chemical Research:
4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyrimidine's unique structure and properties make it a valuable compound for chemical research. It can be used to study various chemical reactions and mechanisms, contributing to the advancement of knowledge in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 148990-17-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,9,9 and 0 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 148990-17:
(8*1)+(7*4)+(6*8)+(5*9)+(4*9)+(3*0)+(2*1)+(1*7)=174
174 % 10 = 4
So 148990-17-4 is a valid CAS Registry Number.
148990-17-4Relevant articles and documents
Design, synthesis, and preliminary bioactivity evaluation of N-benzylpyrimidin-2-amine derivatives as novel histone deacetylase inhibitor
Zhou, Yi,Dun, Yanyan,Fu, Huansheng,Wang, Lei,Pan, Xiaole,Yang, Xinying,Fang, Hao
, p. 936 - 942 (2017/10/05)
Histone deacetylase (HDAC) inhibitors have been identified for the treatment of cancer. Lately, we designed and synthesized a series of substituted N-benzylpyrimidin-2-amine derivatives as potent HDAC inhibitors. In vitro HDAC inhibitory activities and an
Cobalt-catalyzed C-SMe bond activation of heteroaromatic thioethers
Begouin, Jeanne-Marie,Rivard, Michael,Gosmini, Corinne
supporting information; experimental part, p. 5972 - 5974 (2010/11/02)
Cobalt-catalyzed activation of methylthio-substituted N-heterocycles facilitates either cross-coupling reactions with aryl- or benzylzinc compounds or synthesis of the corresponding zinc compounds.
New air-stable catalysts for general and efficient Suzuki-Miyaura cross-coupling reactions of heteroaryl chlorides
Guram, Anil S.,King, Anthony O.,Allen, John G.,Wang, Xianghong,Schenkel, Laurie B.,Chan, Johann,Bunel, Emilio E.,Faul, Margaret M.,Larsen, Robert D.,Martinelli, Michael J.,Reider, Paul J.
, p. 1787 - 1789 (2007/10/03)
New air-stable PdCl2{ PtBu2(p-R-Ph)} 2 (R = H, NMe2, CF3,) complexes represent simple, general, and efficient catalysts for the Suzuki-Miyaura cross-coupling reactions of aryl halides including five-membered heteroaryl halides and heteroatom-substituted six-membered heteroaryl chlorides with a diverse range of arylboronic acids. High product yields (89-99% isolated yields) and turn-over-numbers (10 000 TON) are observed.