148991-61-1Relevant articles and documents
Iron-catalyzed Suzuki-Miyaura coupling reaction of unactivated alkyl halides with lithium alkynylborates
Nakagawa, Naohisa,Hatakeyama, Takuji,Nakamura, Masaharu
supporting information, p. 486 - 488 (2015/05/27)
A Suzuki-Miyaura coupling reaction between unactivated alkyl halides and lithium alkynylborates was performed using an iron-bisphosphine catalyst. The reaction shows high chemoselectivity and is applicable to a broad scope of substrates bearing electrophilic functional groups. A radical probe experiment using cyclopropylmethyl bromide was conducted to investigate the nature of the intermediate in the reaction, showing that an alkyl radical species is generated from the alkyl halide substrate.
Palladium-catalyzed indole, pyrrole, and furan arylation by aryl chlorides
Nadres, Enrico T.,Lazareva, Anna,Daugulis, Olafs
supporting information; experimental part, p. 471 - 483 (2011/04/15)
The palladium-catalyzed direct arylation of indoles, pyrroles, and furans by aryl chlorides has been demonstrated. The method employs a palladium acetate catalyst, 2-(dicyclohexylphosphino)-biphenyl ligand, and an inorganic base. Electron-rich and electron-poor aryl chlorides as well as chloropyridine coupling partners can be used, and arylated heterocycles are obtained in moderate to good yields. Optimization of base, ligand, and solvent is required for achieving best results.
Dehydrogenative silation, isomerization and the control of syn- vs. anti-addition in the hydrosilation of alkynes
Jun, Chul-Ho,Crabtree, Robert H.
, p. 177 - 187 (2007/10/02)
Alkyne hydrosilation has been examined in detail for the catalysts SbF6 (L = PPh3, bq = 7,8-benzoquinolinato) and RhCl(PPh3)3.Factors that favor the normal syn- or the unusual anti-silane addition to the alkynes are examined.Two other unus
