149022-20-8

Basic information

• Product Name: ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT
• Synonyms: 5'-ADENYLIC ACID SODIUM SALT;5-ADENYLIC ACID, SODIUM SALT;5'-AMP 2NA;5'-AMP DISODIUM SALT;5'-AMP-NA2;5'-AMP SODIUM SALT;AMP, 2NA;AMP DISODIUM SALT
• CAS NO: 149022-20-8
• Molecular Formula: C10H12N5Na2O7P
• Molecular Weight: 391.18
• EINECS: 224-961-2
• Product Categories: API intermediates;nucleoside
• Mol File: 149022-20-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 798.5oC at 760mmHg
• Flash Point: 436.7oC
• Appearance: White/crystalline
• Storage Temp.: −20°C
• Solubility: H2O: soluble
• CAS DataBase Reference: ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT(149022-20-8)
• EPA Substance Registry System: ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT(149022-20-8)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• RTECS: AU7481600
• F: 1-10
• Hazardous Substances Data: 149022-20-8(Hazardous Substances Data)

Usage

Uses

Adenosine 5′-monophosphate sodium salt has been used: as a component of reactivation medium to reactivate mouse sperm extracted from caudae epididymides for sperm motility studies as a substrate in signal amplification by reversible exchange (SABRE) method to develop biocompatible SABRE hyperpolarization as a substrate in wheat and Aspergillus niger phytase, assay in luciferase assay to monitor intracellular α-synuclein oligomerization in S1S2 cells to study its effects on induction of therapeutic hypothermia and neuronal damage in a rat model of cardiac arrest (CA) and resuscitation

Biochem/physiol Actions

Adenosine 5′-monophosphate (5′-AMP) is used to enhance flavor in meat and poultry soups. It is also used as a food additive for specific nutritional purposes. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). Along with inosine monophosphate (IMP), AMP mediates the dissociation of skeletal muscle actomyosin to actin and myosin. Therefore, these two factors may be involved in causing the resolution of rigor mortis in muscles.