14903-09-4

Basic information

• Product Name: 7,20-O,O'-di-acetyl-cytochalasin B
• Synonyms: 7,20-O,O'-di-acetyl-cytochalasin B
• CAS NO: 14903-09-4
• Molecular Weight: 563.691
• Mol File: 14903-09-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 7,20-O,O'-di-acetyl-cytochalasin B(CAS DataBase Reference)
• NIST Chemistry Reference: 7,20-O,O'-di-acetyl-cytochalasin B(14903-09-4)
• EPA Substance Registry System: 7,20-O,O'-di-acetyl-cytochalasin B(14903-09-4)

Safety Data

• Hazardous Substances Data: 14903-09-4(Hazardous Substances Data)

Upstream product

• 14930-96-2 cytochalasin B 
• 108-24-7 acetic anhydride 
• 64760-39-0 (16R,20R)-7β,20-diacetoxy-9-hydroxy-16-methyl-1-oxo-10-phenyl-9,23-seco-[13]cytochalasa-6(12),13t,21t-triene-23-thioic acid S-phenyl ester 
• 14930-96-2 cytochalasin B 

Downstream Products

• 64850-72-2 7-O-acetyl-cytochalasin B 
• 14930-96-2 cytochalasin B 
• 14119-72-3 7β,20β-diacetoxy-10-cyclohexyl-16α-methyl-(6ξH)-24-oxa-[14]cytochalasane-1,23-dione 
• 14110-64-6 cytochalasin A 

Relevant articles and documents

CYTOCHALASINS: STRUCTURE-ACTIVITY RELATIONSHIPS

Seven cytochalasins, 7-O-acetylcytochalasin A and two derivatives of cytochalasin B were assayed for Pseudomonas syringae, Bacillus megaterium, and for Geotrichum candidum.Their ability to inhibit the growth of tomato seedlings and their toxicity to brine shrimp (percent larvae mortality) were also investigated.Among the compounds assayed only cytochalasin A showed antibiotic and fungicidal activity.Toxicity to tomato seedlings was exhibited by both - and -macrocyclic cytochalasins, while the activity decreased in the derivatives acetylated on the 7-hydroxy groupand markedly in cytochalasin E.In the brine shrimp bioassay, cytochalasin E was the most active mycotoxin, but generally, at low concentrations, the cytochalasins with the -macrocyclic ring were more active than those with the -macrocyclic ring; cytochalasin A appeared to be the most toxic.

Isolation and structure of the antibiotics Phomin and 5-dehydrophomin

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