1492952-76-7

Basic information

• Product Name: (R)-N- (4-(chlorodifluoromethoxy)phenyl)- 6-(3- hydroxypyrrolidin-1- yl)-5- (1H-pyrazol- 5-yl)nicotinamide
• Synonyms: (R)-N- (4-(chlorodifluoromethoxy)phenyl)- 6-(3- hydroxypyrrolidin-1- yl)-5- (1H-pyrazol- 5-yl)nicotinamide;ABL-001;Asciminib;EOS-61420;L1F3R18W77;UNII-L1F3R18W77;3-Pyridinecarboxamide, N-[4-(chlorodifluoromethoxy)phenyl]-6-[(3R)-3-hydroxy-1-pyrrolidinyl]-5-(1H-pyrazol-3-yl)-
• CAS NO: 1492952-76-7
• Molecular Formula: C20H18ClF2N5O3
• Molecular Weight: 449.8384264
• Mol File: 1492952-76-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-N- (4-(chlorodifluoromethoxy)phenyl)- 6-(3- hydroxypyrrolidin-1- yl)-5- (1H-pyrazol- 5-yl)nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N- (4-(chlorodifluoromethoxy)phenyl)- 6-(3- hydroxypyrrolidin-1- yl)-5- (1H-pyrazol- 5-yl)nicotinamide(1492952-76-7)
• EPA Substance Registry System: (R)-N- (4-(chlorodifluoromethoxy)phenyl)- 6-(3- hydroxypyrrolidin-1- yl)-5- (1H-pyrazol- 5-yl)nicotinamide(1492952-76-7)

Safety Data

• Hazardous Substances Data: 1492952-76-7(Hazardous Substances Data)

Usage

Description

(R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide is a complex organic compound with a unique molecular structure. It is characterized by its chlorodifluoromethoxyphenyl group, hydroxypyrrolidinyl moiety, and pyrazol-5-yl nicotinamide backbone. (R)-N(4-(chlorodifluoromethoxy)phenyl)6-(3hydroxypyrrolidin-1yl)-5(1H-pyrazol5-yl)nicotinamide has potential applications in various fields due to its structural diversity and functional groups.

Uses

Used in Pharmaceutical Industry:
(R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide is used as a potential therapeutic agent for the treatment of cancer and central nervous system (CNS) disorders. Its unique molecular structure allows it to act as an ABL kinase inhibitor and/or an SLC7A11 inhibitor, targeting specific proteins involved in the development and progression of these diseases.
Used in Drug Delivery Systems:
In the field of drug delivery, (R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide can be employed as a component in the design of novel drug delivery systems. Its structural features may enable the development of targeted drug carriers, improving the bioavailability and therapeutic efficacy of the compound in treating cancer and CNS disorders.
Used in Chemical Research:
(R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide can also be utilized in chemical research as a starting material or intermediate for the synthesis of other complex organic molecules. Its unique functional groups and structural features make it a valuable candidate for further exploration and development in various chemical applications.