149519-82-4Relevant articles and documents
Potent in vitro and in vivo inhibitors of platelet aggregation based upon the Arg-Gly-Asp sequence of fibrinogen. (Aminobenzamidino)succinyl (ABAS) series of orally active fibrinogen receptor antagonists
Zablocki,Rico,Garland,Rogers,Williams,Schretzman,Rao,Bovy,Tjoeng,Lindmark,Toth,Zupec,McMackins,Adams,Miyano,Markos,Milton,Paulson,Herin,et al.
, p. 2378 - 2394 (2007/10/02)
Our initial orally active fibrinogen receptor antagonist benzamidinopentanoyl (BAP) series which was discovered through truncation of our iv antiplatelet agent (SC-52012) demonstrated modest oral activity in canine studies (ethyl [5-(4-amidinophenyl)penta