149835-32-5

Basic information

• Product Name: 1H-Benz(f)indol-7-amine, 5,6,7,8-tetrahydro-N,N-dipropyl-
• Synonyms: N,N-Di-n-propyl-5,6,7,8-tetrahydrobenz(f)indol-7-amine;NPTIA
• CAS NO: 149835-32-5
• Molecular Formula: C₁₈H₂₆N₂
• Molecular Weight: 270.418
• Mol File: 149835-32-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 433°Cat760mmHg
• Flash Point: 215.7°C
• Density: 1.05g/cm³
• CAS DataBase Reference: 1H-Benz(f)indol-7-amine, 5,6,7,8-tetrahydro-N,N-dipropyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benz(f)indol-7-amine, 5,6,7,8-tetrahydro-N,N-dipropyl-(149835-32-5)
• EPA Substance Registry System: 1H-Benz(f)indol-7-amine, 5,6,7,8-tetrahydro-N,N-dipropyl-(149835-32-5)

Safety Data

• Hazardous Substances Data: 149835-32-5(Hazardous Substances Data)

Usage

Type of compound

synthetic compound with psychoactive properties

Structural relation

related to hallucinogenic tryptamine compounds such as DMT and 5-MeO-DMT

Derivative of

naturally occurring indole alkaloid found in plants and fungi

Mechanism of action

likely interacts with serotonin receptors in the brain, leading to alterations in perception, mood, and cognition

Safety and legal considerations

should be handled with caution and in accordance with relevant guidelines due to its psychoactive properties.

Upstream product

• 51512-09-5 2-(2-chlorophenyl)acetyl chloride 

Relevant articles and documents

(S)- and (R)-8-(di-n-propylamino)-6,7,8,9-tetrahydro-3H-benz[e]indole-1- carbaldehyde: A new class of orally active 5-HT(1A)-receptor agonists

The enantiomers of 6,7,8,9-tetrahydro-N,N-di-n-propyl-3H-benz[e]indol-8- amine (S-(-)-2b and R-(+)-2b) and their corresponding 1-formyl analogs (S-(- )-6 and R-(+)-6 were prepared and evaluated pharmacologically for serotonergic and dopaminergic activity. The introduction of a formyl group in the 1-position shifted the pharmacological profile of 2b from a mixed D2/5- HT(1A) agonists to a selective 5-HT(1A) agonist (6). The enantiomers of 6 were agonists with full intrinsic activity and had an affinity comparable to that of 8-hydroxy-2-(di-n-propylamino)tetrahydronaphthalene (8-OH-DPAT). In contrast to 8-OH-DPAT, the enantiomers of compound 6 were found to have good oral availability.