150258-70-1

Basic information

• Product Name: diethyl <3,4-bis(benzyloxy)benzyl>phosphonate
• Synonyms: diethyl <3,4-bis(benzyloxy)benzyl>phosphonate
• CAS NO: 150258-70-1
• Molecular Weight: 440.476
• Mol File: 150258-70-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl <3,4-bis(benzyloxy)benzyl>phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl <3,4-bis(benzyloxy)benzyl>phosphonate(150258-70-1)
• EPA Substance Registry System: diethyl <3,4-bis(benzyloxy)benzyl>phosphonate(150258-70-1)

Safety Data

• Hazardous Substances Data: 150258-70-1(Hazardous Substances Data)

Upstream product

• 1699-58-7 3,4-bis(benzyloxy)benzyl alcohol 
• 5447-02-9 3,4-dibenzyloxybenzaldehyde 
• 150258-69-8 1,2-bis(benzyloxy)-4-(bromomethyl)benzene 
• 122-52-1 triethyl phosphite 

Downstream Products

• 462628-81-5 2-(E)-[2-(3,4-dibenzyloxyphenyl)ethenyl]-1,8-dimethoxy-9,10-anthracenedione 
• 150258-77-8 (E)-1-<3,4-bis(benzyloxy)phenyl>-2-<3,4-bis(benzyloxy)phenyl>ethene 

Relevant articles and documents

Synthesis and Protein-Tyrosine Kinase Inhibitory Activity of Polyhydroxylated Stilbene Analogues of Piceatannol

A series of hydroxylated trans-stilbene related to the antileukemic natural product trans-3,3',4,5'-tetrahydroxy stilbene (piceatannol) (1) has been prepared and tested for inhibition of the lymphoid cell lineage-specific protein-tyrosine kinase p56lck, which plays an important role in lymphocyte proliferation and immune function.A number of the analogues displayed enhanced enzyme inhibitory activity relative to the natural product.Reduction of the double bond bridging the two aromatic rings and benzylation of the phenolic hydroxyl groups was found to decrease activity significantly.The most potent compounds in the series proved to be trans-3,3',5,5'-tetrahydroxystilbene, trans-3,3',5-trihydroxystilbene, and trans-3,4,4'-trihydroxystilbene.