15097-49-1 Usage
Description
1-(TRIMETHYLSILYL)PYRROLIDINE, also known as N-trimethylsilyl pyrrolidine, is an organic compound with the chemical formula (CH3)3Si-N-(CH2)3-NH. It is a colorless liquid with a characteristic amine-like odor. 1-(TRIMETHYLSILYL)PYRROLIDINE is known for its reactivity and is commonly used in various chemical reactions due to its silyl group, which can be easily removed under mild conditions.
Uses
1. Used in Chemical Synthesis:
1-(TRIMETHYLSILYL)PYRROLIDINE is used as a reagent for the ring-opening reaction of L-serine β-lactone to yield corresponding 5-amino-L-alanine derivatives. The application reason is that the compound's silyl group can be easily removed, allowing for the formation of the desired product with minimal side reactions.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-(TRIMETHYLSILYL)PYRROLIDINE is used as a precursor for the preparation of iminium triflate salts. The application reason is that these iminium triflate salts are valuable intermediates in the synthesis of various biologically active compounds, such as pharmaceuticals and agrochemicals.
3. Used in Organic Chemistry Research:
1-(TRIMETHYLSILYL)PYRROLIDINE is also used as a protecting group in organic chemistry research. The application reason is that the silyl group can be selectively removed under mild conditions, allowing for the controlled deprotection of amines and other functional groups in complex organic molecules.
4. Used in Material Science:
In material science, 1-(TRIMETHYLSILYL)PYRROLIDINE can be used as a component in the synthesis of novel materials, such as polymers and dendrimers, due to its unique reactivity and the ease of removal of the silyl group.
Check Digit Verification of cas no
The CAS Registry Mumber 15097-49-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,0,9 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 15097-49:
(7*1)+(6*5)+(5*0)+(4*9)+(3*7)+(2*4)+(1*9)=111
111 % 10 = 1
So 15097-49-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H17NSi/c1-9(2,3)8-6-4-5-7-8/h4-7H2,1-3H3
15097-49-1Relevant articles and documents
Palladium and nickel complexes of (P,N)-ligands based on quinolines: Catalytic activity for polymerization and oligomerization
Sirbu, Doina,Consiglio, Giambattista,Gischig, Sebastian
, p. 1143 - 1150 (2006)
Four (P,N)-ligands (1-4) with different steric and electronic properties were synthesized. They were used to prepare the monocationic palladium complexes [Pd(P,N)(CH3)(NCCH3)](PF6) (9-12). The structures of the newly prepared ligand 3 and the neutral palladium complex [Pd(P,N)(CH3)Cl] (10) were analysed by X-ray. The catalytic activity of the palladium complexes toward the copolymerization of styrene and ethylene with CO was low or non-existent. The nickel complexes [Ni(P,N)(1-naphthyl)Cl] (13-16), modified with the ligands 1-4, were prepared and their catalytic activity toward ethylene oligomerization was studied. They showed high activity at ambient temperature and low ethylene pressure (1-12 bar) in the presence of MAO.
An Alumino-Mannich Reaction of Organoaluminum Reagents, Silylated Amines, and Aldehydes
Tarasewicz, Anika,Ensan, Deeba,Batey, Robert A.
supporting information, p. 6071 - 6074 (2018/04/27)
A multi-component coupling using organoaluminum reagents, silylated amines, and aldehydes results in the formation of tertiary amines. Both alkenyl- and alkylaluminum reagents undergo reaction with iminium ion substrates for which the corresponding Petasis borono-Mannich reactions are unsuccessful.
Deoxofluorination reactions using N,N-disubstituted aminodifluorosulfinium tetrafluoroborate salts
Mahé, Olivier,L'Heureux, Alexandre,Couturier, Michel,Bennett, Christopher,Clayton, Simon,Tovell, David,Beaulieu, Francis,Paquin, Jean-Fran?ois
, p. 57 - 60 (2013/11/06)
The synthesis of N,N-disubstituted aminodifluorosulfinium tetrafluoroborate salts is reported, and their behavior as deoxofluorinating agent was evaluated. The deoxofluorination reactions were performed using a primary alcohol, a secondary alcohol and a ketone. Results show that subtle modification of the structure of the reagents can noticeably affect the reactivity and the selectivity in deoxofluorination reactions.
