151049-87-5 Usage
General Description
1H-Pyrazole, 3-bromo-1-methyl-(9CI) is a chemical compound with the molecular formula C4H6BrN2 and a molecular weight of 154.007 g/mol. It is a derivative of pyrazole, which is a heterocyclic aromatic organic compound. This chemical is characterized by the presence of a bromine atom and a methyl group attached to the pyrazole ring. It is commonly used in the field of organic synthesis and pharmaceutical research as a building block for the synthesis of more complex compounds with potential biological activities. Additionally, the presence of the bromine atom makes it useful in various chemical reactions as a halogenation reagent. 1H-Pyrazole,3-bromo-1-methyl-(9CI) is also a useful intermediate in the production of agrochemicals and other fine chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 151049-87-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,0,4 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 151049-87:
(8*1)+(7*5)+(6*1)+(5*0)+(4*4)+(3*9)+(2*8)+(1*7)=115
115 % 10 = 5
So 151049-87-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H5BrN2/c1-7-3-2-4(5)6-7/h2-3H,1H3
151049-87-5Relevant articles and documents
Strategy to Prepare 3-Bromo- and 3-Chloropyrazoles
Fox, Richard J.,Schmidt, Michael A.,Eastgate, Martin D.
, p. 2830 - 2839 (2018/03/09)
A general strategy to prepare substituted 3-bromo- and 3-chloropyrazoles is described. The three-step method involves condensation of crotonates or β-chloro carboxylic acids with hydrazines, followed by halogenation and oxidation. Several condensation and oxidation protocols were developed to enable preparation of a wide variety of 3-halopyrazoles with good to excellent yields and regiocontrol.
HETEROCYCLIC COMPOUND
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Paragraph 0577, (2015/01/18)
The present invention provides an agent for the prophylaxis or treatment of autoimmune diseases (e.g., psoriasis, rheumatoid arthritis, inflammatory bowel disease, Sjogren's syndrome, Behcet's disease, multiple sclerosis, systemic lupus erythematosus etc.) and the like, which has a superior Tyk2 inhibitory action. The present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or a salt thereof.