1510865-19-6

Basic information

• Product Name: 2,3-diphenyl-8-(trifluoromethyl)benzo[b]oxepine
• Synonyms: 2,3-diphenyl-8-(trifluoromethyl)benzo[b]oxepine
• CAS NO: 1510865-19-6
• Molecular Weight: 364.367
• Mol File: 1510865-19-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3-diphenyl-8-(trifluoromethyl)benzo[b]oxepine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-diphenyl-8-(trifluoromethyl)benzo[b]oxepine(1510865-19-6)
• EPA Substance Registry System: 2,3-diphenyl-8-(trifluoromethyl)benzo[b]oxepine(1510865-19-6)

Safety Data

• Hazardous Substances Data: 1510865-19-6(Hazardous Substances Data)

Upstream product

• 1609405-64-2 2-methoxy-4-(trifluoromethyl)-1-vinylbenzene 
• 58914-34-4 2-hydroxy-4-(trifluoromethyl)benzaldehyde 
• 501-65-5 diphenyl acetylene 

Relevant articles and documents

Straightforward assembly of benzoxepines by means of a rhodium(III)- catalyzed C-H functionalization of o-vinylphenols

Readily available o-vinylphenols undergo a formal (5 + 2) cycloaddition to alkynes when treated with catalytic amounts of [Cp*RhCl2] 2 and Cu(OAc)2. The reaction, which involves the cleavage of the terminal C-H bond of the alkenyl moiety, generates highly valuable benzoxepine skeletons in a practical, versatile, and atom-economical manner. Using carbon monoxide instead of an alkyne as reaction partner leads to coumarin products which formally result from a (5 + 1) cycloaddition.