15109-37-2

Basic information

• Product Name: (4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE
• Synonyms: (4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE
• CAS NO: 15109-37-2
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.23588
• Mol File: 15109-37-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 147 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
• Boiling Point: 448.5°C at 760 mmHg
• Flash Point: 225.1°C
• Appearance: /
• Density: 1.228g/cm³
• Vapor Pressure: 3.08E-08mmHg at 25°C
• Refractive Index: 1.613
• PKA: 16.03±0.30(Predicted)
• CAS DataBase Reference: (4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE(15109-37-2)
• EPA Substance Registry System: (4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE(15109-37-2)

Safety Data

• Hazardous Substances Data: 15109-37-2(Hazardous Substances Data)

Usage

Description

(4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE is a chemical compound with the formula C12H12N2O2, belonging to the class of indole derivatives and acetonitrile compounds. It features a benzene ring fused to a five-membered nitrogen-containing ring, along with a nitrile functional group. The molecule also has two methoxy (CH3O-) substituents attached to the benzene ring at the 4 and 7 positions. (4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE may serve various purposes in organic synthesis, pharmaceuticals, and as a research reagent in chemical and biological studies, with its specific applications depending on its unique chemical properties and potential reactions.

Uses

Used in Organic Synthesis:
(4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE is used as a building block for the synthesis of more complex organic molecules. Its unique structure allows for a variety of chemical reactions, making it a versatile compound in the field of organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE is used as an intermediate in the development of new drugs. Its specific properties may contribute to the creation of novel therapeutic agents with potential applications in various medical conditions.
Used as a Research Reagent:
(4,7-DIMETHOXY-1H-INDOL-3-YL)-ACETONITRILE is also utilized as a research reagent in chemical and biological studies. Its distinctive structure and functional groups make it a valuable tool for understanding various chemical and biological processes, potentially leading to new discoveries and advancements in these fields.

InChI:InChI=1/C12H12N2O2/c1-15-9-3-4-10(16-2)12-11(9)8(5-6-13)7-14-12/h3-4,7,14H,5H2,1-2H3

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 92033-00-6 1-(4,7-dimethoxy-1H-indol-3-yl)-N,N-dimethylmethanamine 
• 23876-39-3 4,7-dimethoxylindole 

Downstream Products

• 220034-71-9 tert-butyl (2-{4,7-dimethoxy-1-[(4-methylphenyl)sulfonyl]-1H-indol-3-yl}ethyl)carbamate 
• 220034-57-1 tert-butyl (2-{1-[(4-methylphenyl)sulfonyl]-4,7-dioxo-4,7-dihydro-1H-indol-3-yl}ethyl)carbamate 
• 892112-74-2 tert-butyl (2-{1-(3-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-7-[(4-methylphenyl)sulfonyl]-4,8-dioxo-1,4,7,8-tetrahydro-pyrrolo[3,2-f]indazol-5-yl}ethyl)carbamate 
• 892113-17-6 tert-butyl (2-{1-(3-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-5-[(4-methylphenyl)sulfonyl]-4,8-dioxo-1,4,5,8-tetrahydro-pyrrolo[2,3-f]indazol-7-yl}ethyl)carbamate 
• 892113-84-7 7-(3-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-5-(toluene-4-sulfonyl)-2,3,5,9-tetrahydro-1,5,8,9-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-50-7 9-(3-hydroxy-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-5-[(4-methylphenyl)sulfonyl]-2,3,5,7-tetrahydro-6H-pyrazolo[3,4-h]pyrrolo[4,3,2-de]quinolin-6-one 
• 892113-24-5 5-(toluene-4-sulfonyl)-2,3,5,7-tetrahydro-1,5,7,8-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-57-4 5-(toluene-4-sulfonyl)-2,3,5,9-tetrahydro-1,5,8,9-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 892113-63-2 9-methyl-5-[(4-methylphenyl)sulfonyl]-2,3,5,9-tetrahydro-6H-pyrazolo[4,3-h]pyrrolo[4,3,2-de]quinolin-6-one 
• 892113-31-4 7-methyl-5-(toluene-4-sulfonyl)-2,3,5,7-tetrahydro-1,5,7,8-tetraaza-cyclopenta[e]acenaphthylen-6-one 
• 91557-43-6 2-(4,7-dimethoxy-1H-indol-3-yl)ethylamine 

Relevant articles and documents

Synthesis and antitumor characterization of pyrazolic analogues of the marine pyrroloquinoline alkaloids: Wakayin and tsitsikammamines

A series of aza analogues of the marine alkaloids wakayin and tsitsikammamines A and B have been synthesized. The strategy used was based on [3 + 2] cycloaddition reactions involving 3-ethylamine-indole-4,7-dione and different diazo reagents. All the comp