151427-15-5

Basic information

• Product Name: 5-(4-bromophenyl)-2-(4-pyridyl)oxazole
• Synonyms: 5-(4-bromophenyl)-2-(4-pyridyl)oxazole
• CAS NO: 151427-15-5
• Molecular Weight: 301.142
• Mol File: 151427-15-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-(4-bromophenyl)-2-(4-pyridyl)oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-bromophenyl)-2-(4-pyridyl)oxazole(151427-15-5)
• EPA Substance Registry System: 5-(4-bromophenyl)-2-(4-pyridyl)oxazole(151427-15-5)

Safety Data

• Hazardous Substances Data: 151427-15-5(Hazardous Substances Data)

Upstream product

• 55-22-1 pyridine-4-carboxylic acid 
• 5467-72-1 α-amino-4-bromoacetophenone hydrochloride 
• 99-73-0 para-bromophenacyl bromide 
• 151427-13-3 [2-(4'-bromophenyl)-2-oxoethyl]ammonium bromide 
• 6200-09-5 (4-bromo-phenacyl)-hexamethylenetetraminium; bromide 
• 39178-35-3 isonicotinoyl chloride hydrochloride 
• 151427-14-4 N-(4'-bromophenacyl)isonicotinamide 
• 7644-04-4 4-bromophenacylamine 

Relevant articles and documents

A morpholine group containing pyridine and double protonizing site of the pH of the fluorescent probe, preparation method and application (by machine translation)

The invention provides a pH fluorescence probe with double-protonation loci of pyridine and morpholine groups and a preparation method and application thereof. The structure of the probe is as shown in formula (I) in the specification. The probe has relatively wide pH response within a pH range of 3.1-5.0, the pKa of the probe is 4.05, in addition, the probe has relatively good water solubleness, optical and chemical stability and relatively good ion selectivity and biological compatibility. Fluorescence microimaging tests show that the probe has relatively good cell permeability and pH response, and has very small cytotoxicity.

2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER

Certain oxazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.

Syntheses and Photophysical Properties of Some 5(2)-Aryl-2(5)-(4-pyridyl)oxazoles and Related Oxadiazoles and Furans

A number of 5-aryl-2-(4-pyridyl)oxazoles, a 2-aryl-5-(4-pyridyl)oxazole, the related oxadiazole and furan, several 2-(4-pyridyl)cycloalkanooxazoles, and many of their quaternary salts were prepared.No single standard synthesis was effective for preparation of more than a few of the 25 free bases described; methods often unique to a base were employed.Minor variations in structure sometimes produced large differences in absorption and emission wavelengths, as well as in the magnitude of the extinction coefficient.The salts are of interest as laser dyes, scintillation fluors, biological stains, and shifters for luminescent solar concentrators.