151582-19-3

Basic information

• Product Name: 1,3-Cyclopentanedione, 2-(trifluoroacetyl)- (9CI)
• Synonyms: 1,3-Cyclopentanedione, 2-(trifluoroacetyl)- (9CI)
• CAS NO: 151582-19-3
• Molecular Formula: C7H5F3O3
• Molecular Weight: 194.1080096
• Product Categories: ACETYLHALIDE
• Mol File: 151582-19-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Cyclopentanedione, 2-(trifluoroacetyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Cyclopentanedione, 2-(trifluoroacetyl)- (9CI)(151582-19-3)
• EPA Substance Registry System: 1,3-Cyclopentanedione, 2-(trifluoroacetyl)- (9CI)(151582-19-3)

Safety Data

• Hazardous Substances Data: 151582-19-3(Hazardous Substances Data)

Usage

Type of compound

Diketone derivative

Functional group

Trifluoroacetyl group attached to the cyclopentanone ring

Physical state

Pale yellow solid

Solubility

Insoluble in water, soluble in organic solvents

Applications

Organic synthesis, pharmaceutical research, development of drugs, agrochemicals, and production of other organic compounds

Safety

Handle with care and follow proper safety guidelines

Upstream product

• 3859-41-4 1,3-cyclopentadione 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 1415395-74-2 3-(4-fluorophenylamino)-2-(trifluoroacetyl)cyclopent-2-en-1-one 

Relevant articles and documents

2-Perfluoroalkanoylcyclopentane-1,3-diones. Synthesis and some transformations

2-Perfluoroalkanoylcyclopentane-1,3-diones were synthesized for the first time by acylation of cyclopentane-1,3-dione with perfluorocarboxylic acids in the presence of 1,1′-carbonyldiimidazole or with perfluorocarboxylic anhydrides in the presence of imidazole. 2-Perfluoroalkanoylcyclopentane-1,3- diones were selectively reduced to 2-(1-hydroxyperfluoroalkyl)cyclopentane-1,3- diones by the action of triethylsilane in trifluoroacetic acid in the presence of a catalytic amount of lithium perchlorate. Treatment of the title compounds with oxalyl chloride and subsequent reaction with 2 equiv of primary amine (4-fluoroaniline, 4-fluorobenzylamine, 3,4-difluoroaniline, 3- trifluoromethylbenzylamine) gave the corresponding 3-arylamino-2- perfluoroalkanoylcyclopent-2-en-1-ones. Pleiades Publishing, Ltd., 2012.