15180-02-6 Usage
Description
Amfonelic Acid (AFA) is a dopamine reuptake inhibitor that has been demonstrated to have significant effects on the dopaminergic system in rats. It is known for its ability to completely prevent the effects of methamphetamine on this system, both morphologically and biochemically.
Uses
Used in Pharmaceutical Industry:
Amfonelic Acid is used as a central nervous system stimulant for its ability to inhibit dopamine reuptake, which can be beneficial in treating conditions related to dopamine imbalances.
Used in Research and Development:
AFA is used as a research compound to study the effects of dopamine reuptake inhibition on the central nervous system, particularly in the context of methamphetamine's impact on dopaminergic systems. This can contribute to the development of new treatments for addiction and other dopamine-related disorders.
Pharmacokinetics
Amfonelic acid, a derivative of nalidixic acid, was originally developed as a central nervous system stimulant. It is a highly potent nonamphetamine stimulant whose actions are inhibited by reserpine but not by the tyrosine hydroxylase inhibitor, a-methyltyrosine.
Check Digit Verification of cas no
The CAS Registry Mumber 15180-02-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,8 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 15180-02:
(7*1)+(6*5)+(5*1)+(4*8)+(3*0)+(2*0)+(1*2)=76
76 % 10 = 6
So 15180-02-6 is a valid CAS Registry Number.
InChI:InChI=1/C18H16N2O3/c1-2-20-11-15(18(22)23)16(21)14-9-8-13(19-17(14)20)10-12-6-4-3-5-7-12/h3-9,11H,2,10H2,1H3,(H,22,23)
