15186-48-8

Basic information

• Product Name: (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
• Synonyms: (R)-2,2-DIMETHYL-[1,3]DIOXOLANE-4-CARBALDEHYDE;(R)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBOXALDEHYDE;(R)-2,3-ISOPROPYLIDENE GLYCERALDEHYDE;1,3-DIOXOLANE-4-CARBOXALDEHYDE, 2,2-DIMETHYL-, (R)-;2,3-O-ISOPROPYLIDENE-D-GLYCERALDEHYDE;2,3-O-(R)-ISOPROPYLIDENE-L-GLYCERALDEHYDE;(4R)-2,2-DIMETHYL-1,3-DIOXOLANE-4-CARBALDEHYDE;D-(R)-GLYCERALDEHYDE ACETONIDE
• CAS NO: 15186-48-8
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.14
• EINECS: 1592732-453-0
• Product Categories: pharmacetical;chiral;API intermediates;Chiral Reagents;Heterocycles;Aldehydes;Chiral Building Blocks;Organic Building Blocks;Heterocyclic Building Blocks;Asymmetric Synthesis;Building Blocks;C1 to C6;Carbonyl Compounds;Chemical Synthesis;Chiral Building Blocks;Organic Building Blocks
• Mol File: 15186-48-8.mol
• Article Data: 152

Chemical Properties

• Boiling Point: 139 °C(lit.)
• Flash Point: 143 °F
• Appearance: Colorless to Pale Yellow/Liquid
• Density: 1.045 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.454(lit.)
• Storage Temp.: ?20°C
• Solubility: Difficult to mix.
• CAS DataBase Reference: (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde(15186-48-8)
• EPA Substance Registry System: (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde(15186-48-8)

Safety Data

• WGK Germany: 3
• HazardClass: 6.1
• Hazardous Substances Data: 15186-48-8(Hazardous Substances Data)

Usage

Chemical Properties

Colorless Transparent Liquid

Uses

Different sources of media describe the Uses of 15186-48-8 differently. You can refer to the following data:
1. (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a reactant involved in organic reactions including:? ;Henry condensation reactions1? ;Synthesis of highly functionalized chiral aziridines2? ;Olefination of aldehydes3? ;C-H oxidations4? ;Aldol-type condensations5? ;Synthesis of hydrophilic pyrazine dyes for use as exogenous fluorescent tracer agents6? ;Hosomi-Sakurai reactions7
2. (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde_x000D__x000D_Discontinued, Unstable (cas# 15186-48-8) is a compound useful in organic synthesis.
3. Reactant involved in organic reactions including:Henry condensation reactionsSynthesis of highly functionalized chiral aziridinesOlefination of aldehydesC-H oxidationsAldol-type condensationsSynthesis of hydrophilic pyrazine dyes for use as exogenous fluorescent tracer agentsHosomi-Sakurai reactions

InChI:InChI=1/C6H10O3/c1-6(2)8-4-5(3-7)9-6/h3,5H,4H2,1-2H3

Upstream product

• 3427-24-5 (2S,3E,5S)-1,2,5,6-tetrahydroxy-1,2:5,6-di-O-isopropylidene-hex-3-ene 
• 100227-29-0 5,6-di-O-isopropylidene-D-glucono-1,4-lactone 
• 126694-15-3 4,5-isopropylidene-D-arabinose dibenzyl thioacetal 
• 3969-61-7 1,2;5,6-di-O-isopropylidene-D-mannitol 
• 69-65-8 mannitol 
• 67-64-1 acetone 
• 50-70-4 D-sorbitol 
• 70223-09-5 [(4R,5R)-5-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-1,3-dioxolan-4-yl]methanol 
• 22323-78-0 (1R,2R)-1,2-bis((S)-2,2-dimethyl-1,3-dioxolan-4-yl)ethane-1,2-diol 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 53735-98-1 (1S,2S)-1,2-bis[(R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethane-1,2-diol 
• 64870-23-1 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 312583-58-7 (1S,2S)-1,2-bis(2,2-dimethyl-1,3-dioxolan-4-yl)ethane-1,2-diol 
• 53735-99-2 1,2:5,6-di-O-isopropylidene-D-talo-hexitol 

Downstream Products

• 67010-03-1 (S)-2,3-dihydroxy-propionaldehyde-(2,4-dinitro-phenylhydrazone) 
• 22323-82-6 (S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol 
• 110889-07-1 (R)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-difluoro-4-phenyl-but-3-yn-1-ol 
• 110889-07-1 (S)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-difluoro-4-phenyl-but-3-yn-1-ol 

Relevant articles and documents

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