151864-81-2

Basic information

• Product Name: 3-(4-Carboethoxy)phenyl propanal
• Synonyms: 4-(3-CARBETHOXY)PHENYLPROPANAL;4-(3-OXO-PROPYL)-BENZOIC ACID ETHYL ESTER;3-(4'-CARBOXYPHENYL)-PROPIONALDEHYDE ETHYL ESTER;3-(4-CARBOETHOXY)PHENYL PROPANAL;4-CARBOETHOXYPHENYL PROPANAL;4-CARBOETHOXYPHENYL BUTANAL;4-ETHOXYCARBONYLHYDROCINNAMAL;3-(4-Carbethoxy)Phenylpropanal
• CAS NO: 151864-81-2
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.24
• Product Categories: ACIDHALIDE
• Mol File: 151864-81-2.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 312.448 °C at 760 mmHg
• Flash Point: 135.742 °C
• Appearance: /
• Density: 1.083 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.511
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 3-(4-Carboethoxy)phenyl propanal(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Carboethoxy)phenyl propanal(151864-81-2)
• EPA Substance Registry System: 3-(4-Carboethoxy)phenyl propanal(151864-81-2)

Safety Data

• Hazardous Substances Data: 151864-81-2(Hazardous Substances Data)

Usage

General Description

3-(4-Carboethoxy)phenyl propanal is a chemical compound with the molecular formula C12H14O3. It is an aldehyde derivative that belongs to the class of phenylpropanoids. 3-(4-Carboethoxy)phenyl propanal is commonly used in the fragrance industry due to its pleasant aroma and is often used as a flavoring agent in food products. It is also used in the production of perfumes, cosmetics, and other personal care products. Additionally, 3-(4-Carboethoxy)phenyl propanal has been studied for its potential pharmacological properties, including its antioxidant and antimicrobial activities. Overall, this compound has versatile applications and is valued for its aromatic and functional properties.

InChI:InChI=1/C12H14O3/c1-2-15-12(14)11-7-5-10(6-8-11)4-3-9-13/h5-9H,2-4H2,1H3

Upstream product

• 3054-95-3 acrylaldehyde diethyl acetal 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 107-18-6 allyl alcohol 
• 51934-41-9 4-iodobenzoic acid ethyl ester 

Downstream Products

• 1027288-30-7 C₄₄H₄₃Cl₃N₂O₄S 
• 1196531-95-9 (R,E)-ethyl 4-(3-hydroxyhept-5-enyl)benzoate 
• 848081-14-1 2-amino-5-(4'-ethoxycarbonyl-benzyl)thiophene-3-carboxylic acid ethyl ester 
• 433726-44-4 4-[2-(6-oxo-6,7,8,9-tetrahydro-2,7,9a-triaza-benzo[cd]azulen-1-yl)-ethyl]-benzoic acid ethyl ester 
• 259145-25-0 4-(3-hydroxy-4-nitrobutyl)benzoic acid ethyl ester 
• 151864-82-3 Ethyl 4-(4-hydroxy-3-oxobutyl)benzoate 
• 229470-21-7 4-((E)-4-Nitro-but-3-enyl)-benzoic acid ethyl ester 

Relevant articles and documents

Radical Carbonyl Propargylation by Dual Catalysis

Carbonyl propargylation has been established as a valuable tool in the realm of carbon–carbon bond forming reactions. The 1,3-enyne moiety has been recognized as an alternative pronucleophile in the above transformation through an ionic mechanism. Herein, we report for the first time, the radical carbonyl propargylation through dual chromium/photoredox catalysis. A library of valuable homopropargylic alcohols bearing all-carbon quaternary centers could be obtained by a catalytic radical three-component coupling of 1,3-enynes, aldehydes and suitable radical precursors (41 examples). This redox-neutral multi-component reaction occurs under very mild conditions and shows high functional group tolerance. Remarkably, bench-stable, non-toxic, and inexpensive CrCl3 could be employed as a chromium source. Preliminary mechanistic investigations suggest a radical-polar crossover mechanism, which offers a complementary and novel approach towards the preparation of valuable synthetic architectures from simple chemicals.

Photocatalytic Reductive Radical-Polar Crossover for a Base-Free Corey–Seebach Reaction

A metal-free generation of carbanion nucleophiles is of prime importance in organic synthesis. Herein we report a photocatalytic approach to the Corey–Seebach reaction. The presented method operates under mild redox-neutral and base-free conditions giving the desired product with high functional group tolerance. The reaction is enabled by the combination of photo- and hydrogen atom transfer (HAT) catalysis. This catalytic merger allows a C?H to carbanion activation by the abstraction of a hydrogen atom followed by radical reduction. The generated nucleophilic intermediate is then capable of adding to carbonyl electrophiles. The obtained dithiane can be easily converted to the valuable α-hydroxy carbonyl in a subsequent step. The proposed reaction mechanism is supported by emission quenching, radical–radical homocoupling and deuterium labeling studies as well as by calculated redox-potentials and bond strengths.

Continuous preparing method of aryl propionic aldehyde compound

The invention discloses a continuous preparing method of an aryl propionic aldehyde compound. The method includes the following step of making a compound shown in the formula A and a compound shown inthe formula B have a reaction shown as follows in a tubular reactor in a solvent under the effect of a palladium catalyst, ligand and an organic base to prepare a compound shown in the formula C. Thepreparing method shortens the reaction time, reduces the consumption of the catalyst, is high in safety, ensures the product quality, reduces the cost, reduces the generation of a byproduct (tar), and is more suitable for industrial production.