152123-69-8

Basic information

• Product Name: 2-<(2-(Carboxymethyl)-3-methylphenyl)methyl>naphthoic acid
• Synonyms: 2-<(2-(Carboxymethyl)-3-methylphenyl)methyl>naphthoic acid
• CAS NO: 152123-69-8
• Molecular Weight: 334.372
• Mol File: 152123-69-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-<(2-(Carboxymethyl)-3-methylphenyl)methyl>naphthoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<(2-(Carboxymethyl)-3-methylphenyl)methyl>naphthoic acid(152123-69-8)
• EPA Substance Registry System: 2-<(2-(Carboxymethyl)-3-methylphenyl)methyl>naphthoic acid(152123-69-8)

Safety Data

• Hazardous Substances Data: 152123-69-8(Hazardous Substances Data)

Upstream product

• 84944-47-8 5-Methylhomophthalic anhydride 
• 5454-10-4 N,N-diethyl-1-naphthamide 
• 152123-68-7 1',3'-Dihydrospiro<5-methylisochroman-1,3'-naphtho<1,2-c>furan>-3,1'-dione 

Downstream Products

• 56-49-5 methylcholanthrene 

Relevant articles and documents

A Highly Efficient Synthesis of 3-Methylcholanthrene

A five-step synthesis of 3-methylcholanthrene (1) has been achieved starting from 5-methylhomophthalic anhydride and N,N-diethyl-1-naphthamide in 55percent overall yield.Treatment of a solution of the preformed lithium enolate of 5-methylhomophthalic anhydride (3) with an equimolar solution of 2-lithio-1-naphthamide (4), followed by acid hydrolysis, provides cleanly the spirobislactone 5 in 80percent overall yield.In addition, the synthesis features a unique, highly selective double Friedel-Crafts cyclization of the aryl diacid 2 with PPA to give rise, after acetylation, to keto acetate 6.